Pfizer

Senior Scientist, Process Development

Employer
Pfizer
Location
Andover, Massachusetts
Salary
Competitive
Posted
May 13 2021
Ref
4813310
Position Type
Full Time
Organization Type
Pharma
Job Type
Senior Scientist
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Scientist in Manufacturing Sciences and Technology (MSAT) team at Pfizer, you will be joining a team of scientists across multiple sites focused on Pfizer's portfolio of late stage development and commercial biopharmaceuticals and vaccines. The candidate will work across Pfizer Global Supply (PGS) organization in conjunction with Bioprocess R&D to characterize manufacturing processes using bench scale models to develop and confirm various in-silico tools such as statistical and mechanistic models with increasing application of data science methods.

In this role, the candidate will be responsible for designing and executing bench scale experiments in support of in-silico tools and models. The candidate will also collaborate with manufacturing operations and Bioprocess R&D in digital twin initiatives as a subject matter expert to ensure modeling projects meet the needs of PGS. The colleague may also be involved in innovation and technology development projects that seek to improve production processes both from a process engineering as well as a biological perspective that have the potential to increase process performance and robustness.

How You Will Achieve It

  • Drive the growth of digital technologies at Pfizer for applications in MSAT
  • Contribute to enhancing the ability to efficiently utilize process data
  • Identify projects wherein use of statistical and mechanistic models to characterize a drug substance manufacturing process brings value to the organization
  • Design and assist in the execution of laboratory studies (primarily focusing on upstream processes)
  • Provide expanded analysis and understanding of laboratory results with the application of data science methods
  • Improve the efficiency and robustness of drug substance processes through utilization of scientific software, novel visualization tools, automated data provisioning pipelines
  • Author reports, papers and prepare oral presentations for internal and external audiences
  • Assist in authoring and reviewing of regulatory submissions


Qualifications

Must-Have

  • Bachelor's degree with 9+ years of experience OR Master's degree with 7 years of experience OR Ph. D. with 0-4 years of experience in biotechnology, engineering, data science, statistics, computer science, or related fields
  • Familiarity with bioprocess development and regulatory requirements
  • Experience with data analysis and modeling methods particularly in their application to bioprocess system engineering
  • Experience in advanced data analytics, machine learning methods, and software that provide new ways to build models, diagnose problems, and make informed decisions for biopharmaceutical processes
  • Proficient in benchtop bioreactor operation and associated analytical tools
  • Experience with bench scale cell culture and/or bacterial fermentation
  • Experience in data mining, visualization, integration, and development of multivariate models in the bioprocess context.
  • Proficient in MATLAB, SQL, Python, and R
  • Applicants should be organized, self-motivated, and capable of working independently, and in a collaborative environment
  • Possess strong oral and written communication skills


Nice-to-Have

  • Strong statistics and programming background with proven experience delivering on data science and machine learning applications
  • Experience with the tools to develop, optimize, characterize and scale up process steps


PHYSICAL/MENTAL REQUIREMENTS

Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis and extended use of computers

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Occasional off-hour work and travel

OTHER DETAILS
  • Last Date to Apply: May 20, 2021
  • Eligible for Relocation Package


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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