NIH/NCI, Bethesda, Maryland (US)
First postdoc - salary and behefits
May 12 2021
Position Type
Full Time
Organization Type
Job Type

A postdoctoral position is available within the Optical Microscopy Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in cutting-edge fluorescence microscopy, single molecule tracking and biophysical quantification of dynamics of transcription factors.

Publications in the area of research:

Tatiana S. Karpova et al. Dynamic interactions of a transcription factor with DNA are accelerated  by a chromatin remodeler.  EMBO Reports. 5: 1064-1070, 2004

Tatiana S. Karpova, et al. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008

Ball, D.A et al. Single Molecule Tracking Of Ace1p In Saccharomyces cerevisiae Defines A Characteristic Residence Time For Non-specific Interactions Of Transcription Factors With Chromatin. (2016) Nucleic Acids Res 44:e160.

Mehta G. D et al. Single-Molecule analysis reveals linked cycles of RSC chromatin remodeling and Ace1p transcription factor binding in yeast (2018) Molecular Cell 72: 875-887

                Applicants should contact Dr. Tatiana Karpova ( and submit their CV.

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