A postdoctoral position is available within the Optical Microscopy Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in cutting-edge fluorescence microscopy, single molecule tracking and biophysical quantification of dynamics of transcription factors.
Publications in the area of research:
Tatiana S. Karpova et al. Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeler. EMBO Reports. 5: 1064-1070, 2004
Tatiana S. Karpova, et al. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008
Ball, D.A et al. Single Molecule Tracking Of Ace1p In Saccharomyces cerevisiae Defines A Characteristic Residence Time For Non-specific Interactions Of Transcription Factors With Chromatin. (2016) Nucleic Acids Res 44:e160.
Mehta G. D et al. Single-Molecule analysis reveals linked cycles of RSC chromatin remodeling and Ace1p transcription factor binding in yeast (2018) Molecular Cell 72: 875-887
Applicants should contact Dr. Tatiana Karpova (email@example.com) and submit their CV.