Scientist, Medicinal Chemistry

La Jolla, California
May 12 2021
Position Type
Full Time
Organization Type

We are seeking a highly motivated synthetic chemist who will contribute to the Oncology Medicinal Chemistry Department at Pfizer Worldwide R&D LaJolla, CA. As part of this group, the successful applicant will contribute through innovative synthetic chemistry tothedeliveryof clinical candidates aligned with the Oncology Research portfolio.

  • With the appropriate guidance, develop and enable versatile and modular synthetic routes compatible with rapid new target synthesis, and will validate these routes through reduction to practice.
  • Employ enabled routes to synthesize medicinal chemistry targets within a project.
  • Develop scalable routes to preclinical drug candidates.
  • Liaise with outsourcing point of contact(s) to ensure the efficient transfer of chemistry protocols and scientific guidance to external contract research chemists.
  • Actively participate in discussions, present results in chemistry team meetings and other internal or external science forums.

  • Bachelor's degree in Chemistry and 5+ years of lab-based experience in synthetic organic chemist or Master's degree in Organic Chemistry and 3+ years of lab-based research in synthetic organic chemistry.
  • Strong track record of achievement in synthesis of complex molecules with knowledge of modern synthetic methodologies and analytical and purification techniques.
  • Capable of designing synthetic routes that efficiently meet project needs.
  • Experienced in retrosynthetic analysis, multi-step synthesis, and a range of reaction types, conditions and scales.
  • Demonstrated independence in the laboratory
  • Excellent written and oral communication skills; enthusiasm, integrity, self-motivation, strong interpersonal skills, ability to interact within a multidisciplinary team.
  • Comfortable working in a highly innovative team environment.
  • Can effectively cope with change.
  • Responds well to scientific challenge and applies significant rigor to his or her own work.
  • Will scientifically challenge others in a constructive manner and demonstrate exceptional team working skills.

Other Job Details:
  • Eligible for relocation support
  • Eligible for employee referral bonus


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EEO & Employment Eligibility

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Research and Development


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