Postdoctoral Fellow - Development of Experimental Gene-based Therapies

Duarte, California
May 11 2021
Life Sciences
Position Type
Full Time
Organization Type
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment. City of Hope is a leader in cell therapy currently with 50 CAR-T cell clinical trials ongoing.

Position Summary

A post-doctoral position is available immediately for a highly-motivated individual to join our efforts in developing novel experimental gene-based therapies. We are seeking applicants who are highly motivated, passionate, and innovative, and can work both independently and in a team environment. The project involves applying the latest advances in molecular and cell biology to engineer stem cells to produce nanoparticle exosomes based-RNA therapeutics to regulate gene expression in cell culture and animal models. We aim to focus on targeting transcriptional repression and activation of various genes involved in diseases ranging from chronic obstructive pulmonary disease (COPD) to lung cancer, using novel experimental therapies.

Education, experience, and skills required for consideration:
  • PhD, MD, or MD/PhD with a strong background in molecular and cellular biology with expertise in one or more of the following areas: RNA biology/biochemistry, exosome isolation and manufacturing, genome engineering tools (ZFNs, TALENs, CRISPR/Cas9), epigenetic techniques (eg. ChIP, Bisulfite sequencing), NGS and/or bioinformatics/coding.
  • Candidates with 0-3 years of post-doctoral training will be considered.
  • Interested applicants should submit a CV, brief 1 paragraph summary of research accomplishments and interests and three (3) professional references.

Additional Information:
  • For more information on Dr. Kevin Morris's research please visit here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with a disability.



  • Posting Date: May 10, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

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