Senior Scientist, Upstream RNA Process Development

Pearl River, New York
May 06 2021
Position Type
Full Time
Organization Type
Job Type
Senior Scientist

The Upstream Development group within the Early Bioprocess Development Department in Pfizer Vaccine Research and Development is seeking a Senior Scientist who specializes in molecular biology, with hand on experience and in depth knowledge in generating mRNA using IVT methodologies. Process development expertise is also desirable.

  • Play a senior role in designing experiments to optimize and enhance mRNA product quality and titer
  • Develop method for high throughput generation of mRNA material of comparable quality to large scale manufactured material.
  • Establish monthly work objectives and goals that support the overall program objectives
  • Perform Design of Experiment (DOE) studies to fully characterize processes.
  • Present problems and propose solutions in discussions with group members. Offer insights based on experience to group members to help solve existing problems.
  • Independently analyze experimental data.
  • Author and review DNA/mRNA methodologies
  • Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review.
  • Utilize new technologies and establish those technologies to improve mRNA generation capabilities
  • Make timely notebook entries and review for completed experiments

  • PhD in Biochemical Engineering or related discipline with at least 0-2 years of academic, pharmaceutical, or biotechnology experience, or a relevant BS/MS degree with experience appropriate to the position
  • A strong background in genetics/molecular biology/bioengineering
  • Hands on experience of running IVT experiments
  • Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable. Strong verbal and written communication skills are required.


There are no special physical requirements for this role other than the ability to make aseptic transfers. Mental requirements are a detailed understanding of the scientific subject matter, an ability to make scientific judgments and an ability to perform complex data analysis.


The work requires a flexible work schedule to properly perform cell culture and fermentation manipulations. This may involve the necessity of working outside of core hours and on weekends.

Relocation support available

  • Last Date to Apply:May 28 2020
  • Eligible for Employee Referral Bonus

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development