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Postdoctoral Fellow - Precision Oncology of Gastrointestinal Cancers

Employer
City of Hope
Location
Monrovia, California
Salary
Competitive
Closing date
Jun 7, 2021

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Discipline
Life Sciences, Oncology, Cancer Research
Position Type
Full Time
Organization Type
Healthcare/Hospital

Job Details

Position Summary:
We are seeking multiple Postdoctoral Fellows to become a part of the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair, Department of Molecular Diagnostics and Experimental Therapeutics. Our multidisciplinary research group comprises of basic biologists, gastroenterologists, surgeons, oncologists and bioinformaticians, undertaking a number of collaborative projects involving large international consortia. Our research is focused on translational research as it relates to genomic and epigenomic characterization of various gastrointestinal cancers (GI) including colorectal, pancreatic and gastric cancers, and some of the key research topics include:

Development of circulating DNA/RNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis and predictive response to various therapies.

Study the epigenetic basis of GI cancers (e. g. aberrant DNA methylation, histone modifications and non-coding RNAs.

The genetic basis of early-onset and familial/hereditary colorectal cancers.

The role of tumor microenvironment, stem cells, immune regulation and identification of novel targeted therapies.

The role of extracellular vesicles/exosomes as in cancer pathogenesis and their role as disease biomarkers.

Our group performs cutting-edge research in GI oncology, is very productive and publishes in high-impact journals such as Gastroenterology, JNCI, Clinical Cancer Research, Nature Communications, Annals of Surgery etc.

Key Responsibilities:

Devise, plan, document and advance basic science and translational projects in the relevant research area.

Generate data for grant applications and prepare manuscripts for publication.

Work in close collaboration with other team members and external collaborators, including presentation of progress internally or externally.

Train and supervise technical staff.

Basic education, experience and skills required for consideration:

Recent PhD, MD or MD/PhD, with a strong background and profound knowledge in the field of oncology, cancer biology, immunology or immunotherapy.

Previous experience in working with human specimens and development of novel, innovative cancer biomarkers.

Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications.

Strong team player with excellent communication skills and fluency in English, both spoken and written.

Commitment to the program for at least two-three years.

You will have the unique possibility to drive research towards a novel cancer therapy at the interface of science and translation to the clinic and publish high-impact journals.

Company

City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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