POSTDOCTORAL position in Neurosciences- Mechanobiology- Electronic Microscopy
The laboratory of Nicolas Grillet is recruiting a postdoctoral fellow to work on the molecular mechanisms of sound detection. The hair cells of the inner ear have a mechanotransduction organelle, the hair bundle that is sensitive to minuscule motion. We analyze deaf mutant mice to investigate the role of the mutated protein in sound detection.
This project aims at mapping at nanometric resolution the localization of proteins involved in mechanotransduction in the hair bundle using by immunogold Scanning Electronic Microscopy.
The Grillet lab has expertise in molecular and cellular aspects of the hair bundle function, and in fluorescence and electronic microscopy (scanning, transmission, FIB…) (Trouillet et al, 2021, Journal of Neuroscience.; Wu & Grillet et al., Nature Neuroscience, 2017; Grillet et al., Neuron, 2009).
See our recent cover article in J. Neuroscience (https://www.jneurosci.org/content/41/15.cover-expansion, and lab website for more information (http://grilletlab.stanford.edu/).
We have NIH-funding to localize at high-resolution the mechanotransduction channel complex using electron microscopy.
We are recruiting a post-graduate fellow with a PhD in neuroscience, biophysics, physiology, developmental biology or another relevant field.
Previous experience with electronic microscopy is a plus.
We are expecting high motivation and ability to work independently as well as part of the team.
To apply, please include a CV and a cover letter describing your previous work and career goals, putative starting date, and the contact information for three references to firstname.lastname@example.org.
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