Postdoctoral Research Position - Microbe-host interaction & intervention
The Food Safety and Enteric Pathogens Research Unit (FSEPRU) at the National Animal Disease Center (NADC), Ames, IA, ARS National Program 108-Food Safety performs basic and applied research to characterize and employ pre-harvest strategies to control human food-borne pathogens. The long-term objective of the research is to reduce food-borne pathogen carriage in turkeys, swine, and cattle and develop non-antibiotic intervention strategies to improve intestinal homeostasis and limit the need for antibiotics. Training position will be provided through Oakridge Institute for Science and Education (ORISE) at the NADC and is available to U.S. citizens.
Multiple positions are available to investigate host-microbe interactions with an emphasis on either the bacteria (Salmonella, Campylobacter or Shiga toxin-producing E. coli) or the host (turkey, swine, or cattle). Candidates will perform animal trials to assess intervention approaches (vaccines, in-feed additives) and evaluate changes in host immune status to identify factors likely contributing to colonization control. The incumbent will be part of a multi-disciplinary team including immunology/physiology, microbial ecology, and microbiology to identify and develop novel intervention strategies. Techniques to be used may include RNA-sequencing (including single-cell approaches), flow cytometry, immunohistochemistry, cell-culture, vaccine antigen selection, and microbiology.