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Research Scientist Microinjectionist

Employer
Pfizer
Location
Cambridge, Massachusetts
Salary
Competitive
Closing date
Apr 23, 2021

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Discipline
Health Sciences
Position Type
Full Time
Job Type
Research Scientist
Organization Type
All Industry, Pharma
ROLE SUMMARY

Pfizer's in vivo functional genomics unit is focused on rapid generation of transgenic mouse models for validation of new drug targets, mechanistic understanding of disease pathology and preclinical testing. The unit applies the latest technical developments in gene editing and transgenic technology to create First-In-Class genetically engineered mouse models (GEMMs).

The position will be responsible for speedy generation of GEMMs through genome editing in mouse zygotes and will take part in testing and implementation of the latest transgenic technologies.

ROLE RESPONSIBILITIES
  • Support the procedures involved in mouse model generation (embryo production via superovulation, IVF, cryopreservation, electroporation/microinjection, transfer surgery, post-operative care, sampling, genotyping and breeding of animals).
  • Project tracking and colony management.
  • Support the testing of new and experimental technologies for creation of animal models, together with other members of the group.
  • Rigorous compliance with the letter and spirit of all animal welfare and safety protocols.


QUALIFICATIONS

BASIC QUALIFICATIONS
  • Bachelor's degree in biology or related field with 7 years of experience, or Master's degree with 5 years of experience.
  • >3 years of experience with microinjection, implantation surgery and breeding.
  • Good understanding of all the scientific and practical steps involved in making transgenic models.
  • Ability to engage closely in multiple projects and to track record of timely execution.
  • Excellent interpersonal and communication skills; ability to maintain productive and congenial collaborations in a fast-paced environment.
  • Devotion to advancing team goals and enthusiasm for contributing to the mission of drug discovery.
  • Able to spend significant time at microscope.


PREFERRED QUALIFICATIONS
  • >5 years of experience with microinjection and implantation surgery.
  • Experience in cryopreservation and IVF.
  • Solid understanding of basic molecular biology techniques used for genotyping.


Other Job Details:
  • Eligible for Relocation Package: YES
  • Eligible for Employee Referral Bonus: YES


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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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