Postdoctoral Fellow, Tumor Cellular Immunology and Cancer Vaccines, NCI, NIH

A highly motivated postdoctoral fellow is sought to work on tumor immunology with a strong background in biology, preferentially molecular and cellular immunology.  The tumor immunology team in the laboratory is exploring mechanisms of improving vaccines and immunotherapy for cancer, especially by discovering new principles to enhance and steer T cell immune responses.  The group is focusing on negative immunoregulatory mechanisms used for immune evasion by cancer cells.  The postdoctoral fellow will work on a project to understand the effect of matching MHC alleles on the anti-tumor immunity of cancer vaccines and  combinations of vaccines with blockers of negative regulatory mechanisms of tumor immunity, especially the mechanisms initiated by NKT cells.  Group members also have an opportunity to gain knowledge of HIV/mucosal immunology by interacting with the HIV research group in the lab.