Senior Scientist, Analytical R&D

Andover, Massachusetts
April 14 2021
Position Type
Full Time
Organization Type
Job Type
Senior Scientist
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.


Pfizer is seeking a talented individual to join our Analytical Research and Development organization to enable development of biological therapeutics in Andover, MA. The qualified candidate will be responsible for applying analytical methods in the assessment of product quality, detection of impurities, and protein characterization. The candidate will work with scientists performing testing in the R&D and/or regulated settings in support of clinical drug candidates. The candidate will also contribute to method development, transfer, verification, and qualification in support of process and formulation development for biotherapeutics including monoclonal antibodies, fusion proteins, bispecific antibodies, and other biological modalities.

  • Develop analytical methodologies and strategies needed to progress biotherapeutic products in the pipeline; this includes method development, process support, formulation and stability support, product characterization and method qualifications.
  • The candidate will be responsible for becoming proficient in a breadth of analytical methodologies including HPLC and electrophoresis assays and applying these methods to a broad range of biotherapeutics for early and late stage products.
  • The candidate will provide data interpretation to their teams and to their customers, and he or she will revise, review, and author test methods.
  • This role will require the candidate to be able to provide technical expertise to junior level colleagues.
  • The candidate should be able to develop and deliver scientific presentations, and he or she should also be able to prepare clear and concise technical reports and contribute to regulatory filings.
  • The candidate should have experience with state-of-the-art protein characterization and analysis techniques.
  • It is desirable for the candidate to have working knowledge of mass spectrometry.

  • Ph.D. in analytical chemistry, biotech, biochemistry, or related discipline; or Master's degree in analytical chemistry, biochemistry, or related discipline and at least 3-6 years of experience in an analytical laboratory focused on analysis and/or characterization of biopharmaceutical products.
  • 1-3 years (Ph.D.) of post-doctoral or industrial experience working with biological molecules using an array of analytical methodologies (3-5 years for MS).
  • Good interpersonal and collaborative skills, excellent communication skills (verbal and written), and be highly motivated with the desire to continuously learn and develop.
  • Candidate should be self-motivated, goal driven, and should be able to work effectively on teams to progress projects.
  • The candidate's ability to take initiative and manage projects is highly desirable.
  • Excellent verbal and written communication skills are required for this position.
  • A candidate with strong organizational, multi-tasking and problem-solving skills is required.
  • The candidate must be committed to high quality work, attention to detail.
  • The candidate must have a team player mentality and be able to work in a highly flexible, matrixed environment.

  • Experience using some or all the following techniques: all modes of HPLC, SDS-PAGE, iCE and/or CE for analysis and/or characterization of biologicals including; proteins, antibodies, peptides, and conjugates. Industrial experience and an understanding of the drug development process are desired. Other desired attributes are:
  • Experience with characterization and method development for bispecific antibodies.
  • Experience with state-of-the-art protein characterization and analysis techniques, including mass spectrometry.
  • Experience with method development and qualification.
  • Experience authoring CMC sections of regulatory documents.

  • Position requires occasional light lifting and periods of standing, sitting or walking.
  • A bility to perform mathematical calculations and ability to perform complex data analysis .

  • Occasional work-related travel may be needed.

Other Job Details:
  • Last Date to Apply for Job: April 27, 2021
  • Eligible for Relocation Package: YES
  • Eligible for Employee Referral Bonus: YES

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development