Postdoctoral Fellow - Coler Lab
We seek an enthusiastic and collaborative postdoctoral fellow to join The Coler Translational Immunology Lab. The successful candidate will play a key role in characterizing functionality of immune cells in the context of tuberculosis, nontuberculous mycobacteria and positive strand RNA viruses e.g., SARS-CoV-2. Previous experience in human immunology and cellular immunoassays, including multiparametric flow cytometry, is required. Excellent organizational and communication skills are essential.
• A PhD in immunology or related discipline.
• Experience in microbiology and/or infectious diseases.
- Experience and skills with PBMC processing, humoral, and/or cellular immunology and human T- and B-cell
based functional assays (e.g., >10-color flow cytometry panels, ELISPOT, ELISA and antibody neutralization).
- Deep understanding of immunology and/or human biomarker research.
- A strong publication track record.
• Experience working under Biosafety Level 2 or 3 (BSL-2/BSL-3) conditions.
• Excellent oral and written communication skills in English.
• Proficiency in MS Office, scientific data/graphics programs, and biostatistics.
• Must be self-motivated, highly organized and be able to work in a team environment.
• Assessment of immunological endpoints in vaccine clinical trials including assay development and validation.
- Contribute to writing clinical study reports, statistical analysis plans and grant applications.
- Perform specimen processing and shipping for domestic and international sites.
- Work closely under supervision to implement research projects that further the understanding and development of effective vaccines.
• Committed participation as a team member to support experimental design, immunoassay development and methodology following scientific literature review, quality standards and discussion with peers, as required.
- Responsible for following Standard Operating Procedures and development/optimization/ qualification/validation reports for immunoassays.
- Responsible for performing assay development, optimizations, and validations in collaboration with others.
- Participate in laboratory audits to ensure GCLP-like compliance and assist with clinical training activities.
- Records procedures, outcomes and observations in lab notebook following established guidelines.
• Utilize established mathematical and scientific techniques to compile, critically analyze and interpret
• Communicate with research management on a regular basis.
• Prepare manuscripts for publication in peer reviewed journals.
• Presents research at group and internal/external scientific meetings.
• Contributes to maintenance of the sample biorepository including sample tracking procedures.