Postdoctoral Fellow - Coler Lab

Seattle, Washington State
DOE + Benefits
April 08 2021
Position Type
Full Time
Organization Type
Job Type

We seek an enthusiastic and collaborative postdoctoral fellow to join The Coler Translational Immunology Lab.  The successful candidate will play a key role in characterizing functionality of immune cells in the context of tuberculosis, nontuberculous mycobacteria and positive strand RNA viruses e.g., SARS-CoV-2.  Previous experience in human immunology and cellular immunoassays, including multiparametric flow cytometry, is required.  Excellent organizational and communication skills are essential.


•             A PhD in immunology or related discipline.

•             Experience in microbiology and/or infectious diseases.

  •        Experience and skills with PBMC processing, humoral, and/or cellular immunology and human T- and B-cell

               based functional assays (e.g., >10-color flow cytometry panels, ELISPOT, ELISA and antibody neutralization).

  •        Deep understanding of immunology and/or human biomarker research.
  •        A strong publication track record.

•             Experience working under Biosafety Level 2 or 3 (BSL-2/BSL-3) conditions.

•             Excellent oral and written communication skills in English.

•             Proficiency in MS Office, scientific data/graphics programs, and biostatistics.

•             Must be self-motivated, highly organized and be able to work in a team environment.

Primary Responsibilities:

•             Assessment of immunological endpoints in vaccine clinical trials including assay development and validation.


  • Contribute to writing clinical study reports, statistical analysis plans and grant applications.
  • Perform specimen processing and shipping for domestic and international sites.
  • Work closely under supervision to implement research projects that further the understanding and development of effective vaccines.

•             Committed participation as a team member to support experimental design, immunoassay development and methodology following scientific literature review, quality standards and discussion with peers, as required.


  • Responsible for following Standard Operating Procedures and development/optimization/ qualification/validation reports for immunoassays.
  • Responsible for performing assay development, optimizations, and validations in collaboration with others.
  • Participate in laboratory audits to ensure GCLP-like compliance and assist with clinical training activities.
  • Records procedures, outcomes and observations in lab notebook following established guidelines.

•             Utilize established mathematical and scientific techniques to compile, critically analyze and interpret


•             Communicate with research management on a regular basis.

•             Prepare manuscripts for publication in peer reviewed journals.

•             Presents research at group and internal/external scientific meetings.

•             Contributes to maintenance of the sample biorepository including sample tracking procedures.