Postdoctoral Fellow - Coler Lab

Location
Seattle, Washington State
Salary
DOE + Benefits
Posted
April 08 2021
Position Type
Full Time
Organization Type
Non-Profit
Job Type
Postdoc

We seek an enthusiastic and collaborative postdoctoral fellow to join The Coler Translational Immunology Lab.  The successful candidate will play a key role in characterizing functionality of immune cells in the context of tuberculosis, nontuberculous mycobacteria and positive strand RNA viruses e.g., SARS-CoV-2.  Previous experience in human immunology and cellular immunoassays, including multiparametric flow cytometry, is required.  Excellent organizational and communication skills are essential.

Qualifications:

•             A PhD in immunology or related discipline.

•             Experience in microbiology and/or infectious diseases.

  •        Experience and skills with PBMC processing, humoral, and/or cellular immunology and human T- and B-cell

               based functional assays (e.g., >10-color flow cytometry panels, ELISPOT, ELISA and antibody neutralization).

  •        Deep understanding of immunology and/or human biomarker research.
  •        A strong publication track record.

•             Experience working under Biosafety Level 2 or 3 (BSL-2/BSL-3) conditions.

•             Excellent oral and written communication skills in English.

•             Proficiency in MS Office, scientific data/graphics programs, and biostatistics.

•             Must be self-motivated, highly organized and be able to work in a team environment.

Primary Responsibilities:

•             Assessment of immunological endpoints in vaccine clinical trials including assay development and validation.

 

  • Contribute to writing clinical study reports, statistical analysis plans and grant applications.
  • Perform specimen processing and shipping for domestic and international sites.
  • Work closely under supervision to implement research projects that further the understanding and development of effective vaccines.

•             Committed participation as a team member to support experimental design, immunoassay development and methodology following scientific literature review, quality standards and discussion with peers, as required.

 

  • Responsible for following Standard Operating Procedures and development/optimization/ qualification/validation reports for immunoassays.
  • Responsible for performing assay development, optimizations, and validations in collaboration with others.
  • Participate in laboratory audits to ensure GCLP-like compliance and assist with clinical training activities.
  • Records procedures, outcomes and observations in lab notebook following established guidelines.

•             Utilize established mathematical and scientific techniques to compile, critically analyze and interpret

              data.

•             Communicate with research management on a regular basis.

•             Prepare manuscripts for publication in peer reviewed journals.

•             Presents research at group and internal/external scientific meetings.

•             Contributes to maintenance of the sample biorepository including sample tracking procedures. 

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