Pfizer

Sr. Scientist- Polymer/Lipid Drug Delivery(DPDD)

Employer
Pfizer
Location
Andover, Massachusetts
Salary
Competitive
Posted
April 04 2021
Ref
4810193
Position Type
Full Time
Organization Type
Pharma
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

RoleSummary

The incumbent candidate will bring to this laboratory-based role the requisite expertise for developing, evaluating and characterizing novel drug delivery formulations for the delivery of diverse biotherapeutic modalities including (but not limited to) lipid nanoparticles, polymeric nanoparticles, vaccines, and protein-based therapies, and other targeted delivery strategies. This individual functions as a lipid/polymer chemist and drug delivery scientist and is responsible for working in a team-based environment to meet project deadlines. The incumbent displays strong scientific and technical expertise in various aspects of polymer chemistry, organic chemistry, analytical and protein chemistry. Incumbent must have the scientific commitment and strong desire to make impactful scientific and technical contributions within the Pharmaceutical Research & Development team and the respective project teams.

Role Responsibilities
  • Provide scientific and technical expertise in lipid/polymer chemistry and analytical methods of characterization of lipids and polymers
  • Hands-on experimentation towards the preparation of innovative drug delivery solutions including, but not limited to, lipids or for use in nanoparticles or other delivery technologies
  • Utilize chromatographic, biophysical and other analytical methods for characterization in order to fully understand quality attributes for early research studies
  • Manage laboratory, including care and upkeep of complex lab instrumentation, oversight of important reagent/sample inventory, and strategic scientific instrument capital planning
  • Data management, including notebook keeping, processing of data, writing reports on projects and presenting results to team members and to larger diverse audiences


Basic Qualifications
  • Ph.D. with 0-3 years relevant industrial experience, M.S. with 3-6 years relevant experience or BS/BA with 5-8 years relevant experience
  • Subject matter expertise in lipid or polymer chemistry, linkers and techniques is essential
  • Hands on experience with organic synthesis, purification and analysis of lipids and/or polymers is required
  • Analytical expertise with HPLC/UPLC (CAD, ELSD, RI), GPC/SEC, DLS, Mass Spectrometry (TOF or MALDI) and/or AF4-MALS is required
  • Some experience with nanoparticles or liposomes and particle characterization such as particle sizing and counting is required
  • Excellent interpersonal skills and ability to work with others in a dynamic and highly collaborative environment is essential


Preferred Qualifications
  • Expertise in oligonucleotide, protein and/or peptide analytical and purification techniques such as Capillary Gel Electrophoresis, HPLC/UPLC, TFF/HF, and/or other methods is highly recommended
  • Working knowledge in aqueous bioconjugation reactions and reagents for both small molecules and/or biologics is highly recommended
  • Some experience with other drug delivery technologies is a plus
Relocation support available

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development