Pfizer

Senior Scientist Early BioProcess Development

Employer
Pfizer
Location
Pearl River, New York
Salary
Competitive
Posted
April 01 2021
Ref
4808810
Position Type
Full Time
Organization Type
Pharma
Job Type
Senior Scientist
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

This is a laboratory-based position within the Vaccine Research and Development - Analytical Development group. The primary focus of this role is to develop robust analytical assays, and to design and execute assay qualification and transfer studies in support of early vaccine development for a range of adjuvants and antigens. Assays include standard analytical separations (HPLC, CE, etc.) and spectroscopic techniques (UV, DLS). In addition, the candidate will be expected to provide analytical support for bioprocess and formulation development of new adjuvants and antigens by performing routine and non-routine sample testing.

How You Will Achieve It
  • Identify key quality attributes for new vaccine candidates such as liposomes and lipid nanoparticles and contribute to the selection of analytical methodology and techniques to be used.
  • Provide lab-based assay development support.
  • The candidate should be familiar with the ICH guidelines for method qualification and would be expected to design, plan, and execute assay development, qualification and transfer studies with a high degree of independence.
  • Establish and utilize new technologies, where required, to enhance our characterization toolbox and understanding about the adjuvants being developed.
  • The individual will perform routine and non-routine sample analysis support for vaccine development.
  • Plan and prioritize own assay development and analysis activities to ensure timelines are met.
  • Author and review laboratory methods and reports.
  • The individual is expected to contribute and participate in general laboratory maintenance activities (such as maintenance of equipment, managing laboratory waste.


QUALIFICATIONS
  • PhD in Chemistry, Biochemistry, or a related discipline with at least 2 years of academic, pharmaceutical, or biotechnology experience or an MS plus 7 years of related work experience is required.
  • A strong background in separation-based analytical techniques and method qualification following ICH guidelines is essential.
  • Experience with applying these methodologies to liposomal and LNP adjuvants is strongly preferred.
  • Proficiency and ability to utilize analytical techniques such as HPLC separation methods, CE, DLS and UV-Vis to develop methods to characterize potential adjuvant candidates.
  • Experience with SEC-MALS and MS is a plus.
  • Experience in adjuvant and antigen analytical assay development, and a background in liposomes and lipid nano particles is considered as a major plus.
  • Strong verbal and written communication as well as excellent documentation skills are required.


PHYSICAL/MENTAL REQUIREMENTS
  • Standard laboratory conditions - sitting, standing, primarily lab based.
  • Ability to perform mathematical calculations and ability to perform complex data analysis.


NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
  • 40 hours per week


Other Job Details:
  • Last Date to Apply for Job: April 16, 2021
  • Eligible for Employee Referral Bonus: YES
  • Eligible for Relocation: YES


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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