GSK

Scientist, Physico-Chemical Characterization

Employer
GSK
Location
Rockville, MD
Salary
Competitive
Posted
March 09 2021
Ref
281897
Organization Type
Pharma
Are you energized by a challenging role in biology, where scientific demand is driving team growth? If so, this Scientist, Physico-Chemical Characterization, role would be a great opportunity to consider.

Within the Analytical Development US, the Scientist, PhysicoChemical Characterization will serve as Subject Matter Expert (SME) in state-of-the-art spectroscopy (Mass /Optical) and sizing technologies and its application to vaccine development. The Scientist will be responsible for the design, development of qualitative/quantitative spectroscopic methodologies and data analysis approaches. The role will support drug substance/drug product characterization, product and process development, the development and transfer of release methods for GMP testing.

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…

  • Will provide support and technical knowledge in dealing with regulatory filings specifically related to spectroscopy and product characterization.

  • Collaborates with other development functions (locally and globally) to meet project deliverable and timelines.

  • Lead the in evaluation and developability of Mass spectroscopy, Fluorescence, FTIR, Raman, CD, MALS, AUC, Calorimetry based assay development.

  • Serve as subject matter expert on new and existing mass spectroscopy and spectroscopy platforms.

  • Explore new materials, methods, instrumentation, and equipment

  • Plans, designs and execute the studies when assigned to the project.

  • Present results internally and externally at industry and scientific conferences.

  • Publish in top tier journals.

  • Follow GSK procedures and core values



Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:
  • MS (6+ years) / Ph.D. (0-3+) years or equivalent experience in mass spectrometry, bio/analytical, biochemistry, pharmaceutical chemistry.
  • Experience with high resolution analysis of protein, carbohydrates, lipids, polynucleotides (DNA/RNA) and nanoparticle characterization.
  • Operating and maintaining state-of- the-art MS instruments including, but not limited to Thermo Orbitrap, Waters Xevo QTOF, AB
  • Experience in operating and maintain biophysical characterization instrumentation.


Preferred Qualifications:

If you have the following characteristics, it would be a plus:
  • A detail-oriented self-starter and be able to work independently under minimum supervision
  • Experience with, liquid handling systems, and robotic automation.
  • Hands-on experience with applying MS- based methodologies such as H/D exchange, chemical crosslinking, SILAC, MRM, top down/Bottom up, peptide mapping, PTM characterization, HCP profiling, glycan analysis, disulfide bond mapping.


Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.


*This is a job description to aide in the job posting, but does not include all job evaluation details.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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