Doctoral student in Molecular Genomics

Employer
SciLifeLab
Location
Stockholm, Sweden (SE)
Salary
monthly salary according to KTH’s Doctoral student salary agreement.
Posted
March 23 2021
Organization Type
Academia
Job Type
PhD Fellowship

We are seeking an excellent PhD student who has gained experience in wet-lab and/or computational analyses in cell biology, molecular biology, gene technology or genetics. The position is open at the Science for Life Laboratory and KTH Royal Institute of Technology (Stockholm, Sweden), in the laboratory of Molecular Genomics. We investigate chromatin dynamics and RNA synthesis across genes and enhancers, analysing how cells establish, maintain and adapt transcriptional programs. As models, we use rapid signal responses, differentiation and disease progression in human and mouse. The position is expected to begin during summer or fall 2021. Please apply via the recruiter site linked below.

School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH 

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH) is one of the five schools of KTH and a strong constellation for research and education in the broader areas of health, environment, energy and materials. See our homepage: https://www.kth.se/en/cbh

This position is located at Science for Life Laboratory. For more information please se our homepage: https://www.scilifelab.se

Project description 

Third-cycle subject: Gene Technology

The Molecular Genomics lab investigates genome regulation, chromatin architecture and transcriptional mechanisms. We use and develop techniques that track nascent transcription at a nucleotide-resolution, measuring rate-limiting steps of transcription at genes and enhancers. The broad scope of Your project is to gain mechanistic understanding on how chromatin architecture and transcription are coordinated at genes and enhancers, and how cells orchestrate transcriptional program in physiologically relevant settings, such as acute stress responses, differentiation and disease progression.

The Molekylar Genomics laboratory is part of Science for Life Laboratory (http://www.scilifelab.se/), a national center for Natural Sciences in Sweden.

Job assignments 

As a PhD student in Molecular Genomics, you will investigate genome organisation, mechanisms of transcription and cellular responses. You will use and develop advanced biochemical methods and data analytical tools, including run-on, ChIP-seq and ATAC-seq based genome-wide assays. The successful candidate will take a strong lead on planning and performing original research in the fields of cell and molecular biology, genomics and gene technology. You are driven and motivated to understand how transcription is orchestrated at genes and enhancers, and how developmental processes, rapid cellular responses and transcriptional memory are mechanistically regulated in cells and organisms. 

Supervision: Assistant Professor, Anniina Vihervaara.

What we offer

Eligibility

To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:

  • passed a degree at advanced level,
  • completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits at advanced level, or
  • in any other way acquired within or outside the country acquired essentially equivalent knowledge.
  • Requirements for English equivalent to English B/6, read more here

Requirements

  • Master of Sciences degree in cell biology, molecular biology, biotechnology, bioinformatics or a related topic.
  • Laboratory experience in cell and molecular biology, biochemistry or biotechnology
  • Experiecne in analysing genome regulation, mRNA expression or protein levels.

Prefered qualifications

  • Biochemical or data analytical skills in deep-sequencing techniques (e.g. ChIP-seq, CUT & Run, RNA-seq, ATAC-seq).
  • Experience in mass spectorometry or genome editing (e.g. CRISPR, cloning).
  • Experience in analysing cellular responses or developmental processes

Selection

In order to succeed as a doctoral student at KTH you need to be goal oriented and persevering in your work. During the selection process, candidates will be assessed upon their ability to:

  • independently pursue his or her work
  • collaborate with others,
  • have a professional approach and
  • analyse and work with complex issues.

After the qualification requirements, great emphasis will be placed on personal competency.

Target degree: Doctoral degree

Information regarding admission and employment

Only those admitted to postgraduate education may be employed as a doctoral student. The total length of employment may not be longer than what corresponds to full-time doctoral education in four years ' time. An employed doctoral student can, to a limited extent (maximum 20%), perform certain tasks within their role, e.g. training and administration. A new position as a doctoral student is for a maximum of one year, and then the employment may be renewed for a maximum of two years at a time.

Union representatives

You will find contact information for union representatives on KTH's website.

Doctoral section (Students’ union on KTH Royal Institute of Technology)

You will find contact information for doctoral section on the section's website.

Application

Apply for the position and admission through KTH's recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/entral European Summer Time).

Applications must include the following elements:

  • CV including your relevant professional experience and knowledge.
  • Application letter with a brief description of why you want to pursue research studies, about what your academic interests are and how they relate to your previous studies and future goals. (Maximum 2 pages long)
  • Copies of diplomas and grades from previous university studies and certificates of fulfilled language requirements (see above). Translations into English or Swedish if the original document is not issued in one of these languages.
  • Representative publications or technical reports. For longer documents, please provide a summary (abstract) and a web link to the full text.
  • Contact information of 1-2 References.

Other information

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process please read here.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

 

Similar jobs

Similar jobs