Postdoctoral fellow

Location
San Francisco, California
Salary
Commensurate with experience
Posted
March 15 2021
Position Type
Full Time
Organization Type
Academia
Job Type
Postdoc

Two to three funded postdoctoral positions are available in the Hasenstaub and Stryker laboratories at UCSF, to study A) the neural circuitry supporting cross-modal interactions in the mouse auditory and visual cortices and B) the mechanisms of sensory plasticity following interneuron precursor transplantation.  

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POST-DOCTORAL POSITIONS: CIRCUITRY SUPPORTING CROSS-MODAL INTERACTIONS IN THE MOUSE AUDITORY AND VISUAL CORTEX

The Hasenstaub lab is seeking one or two creative, productive, and motivated postdoctoral fellows to join an NIH-funded research project to study the circuit bases of behavioral and neural cross-modal interactions in the auditory and visual cortices.  Appointees will join a vibrant, interactive and diverse neuroscience community with frequent cross-group interactions including joint lab meetings, journal clubs, and many jointly mentored trainees.

Ideal candidates will be self-motivated, curious, enthusiastic, prepared to work in a collaborative environment, and committed to rigorous, reproducible science.  Experience in one or more of the relevant techniques is essential: these include behavioral training and psychophysical analyses, auditory and visual stimulus design, in vivo electrophysiology, in vitro patch clamp, theoretical and computational analysis, molecular circuit dissection tools (optogenetics, DREADDs, etc), and/or long-term manipulations of the sensory environment.  Experience with transgenic mouse lines, single-cell sequencing methods, and histology/anatomy will be helpful but is not required.  First-author publications (or manuscripts in press) are required, as well as interest and capacity to compete for postdoctoral fellowships.  We welcome candidates from diverse backgrounds.  

If you are interested, please check out these recent publications:

  • “Visual Information Present in Infragranular Layers of Mouse Auditory Cortex.” J Neurosci 2018 https://pubmed.ncbi.nlm.nih.gov/29440554/
  • “Cortical Interneurons Differentially Regulate the Effects of Acoustic Context.”  Cell Rep. 2017 https://pubmed.ncbi.nlm.nih.gov/28746863/
  • “Movement and VIP Interneuron Activation Differentially Modulate Encoding in Mouse Auditory Cortex.”  eNeuro, 2019 https://pubmed.ncbi.nlm.nih.gov/31481397/ 

To apply, please send CV and statement of interest to andrea.hasenstaub@ucsf.edu.

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POST-DOCTORAL POSITIONS: MECHANISMS OF SENSORY PLASTICITY FOLLOWING INTERNEURON PRECURSOR TRANSPLANTATION 

The labs of Andrea Hasenstaub and Michael Stryker are seeking one or two creative, productive, and motivated postdoctoral fellows to join an NIH-funded research project to study the circuit and cellular basis of sensory plasticity following transplantation of embryonic interneuron precursors into the postnatal brain (a joint project with Arturo Alvarez-Buylla). Appointees will join a vibrant, interactive and diverse neuroscience community with frequent cross-group interactions including joint lab meetings, journal clubs, and many jointly mentored trainees. 

Ideal candidates will be self-motivated, curious, enthusiastic, prepared to work in a collaborative environment, and committed to rigorous, reproducible science. Experience in one or more of the relevant techniques is essential: these include in vivo electrophysiology, in vivo 2-photon imaging, in vitro patch clamp, theoretical and computational analysis, molecular circuit dissection tools (optogenetics, DREADDs, etc), and/or long-term manipulations of the sensory environment. Experience with transgenic mouse lines, single-cell sequencing methods, and histology/anatomy will be helpful but is not required. First-author publications (or manuscripts in press) are required, as well as interest and capacity to compete for postdoctoral fellowships. We welcome candidates from diverse backgrounds.  

If you are interested, please check out these recent publications: 

  • “Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.” Elife, 2020 https://pubmed.ncbi.nlm.nih.gov/32633719/ 
  • “Transplanted Cells Are Essential for the Induction But Not the Expression of Cortical Plasticity”, J. Neurosci 2019 https://pubmed.ncbi.nlm.nih.gov/31391263/ 
  • “Vesicular GABA transporter is necessary for transplant-induced critical period plasticity in mouse visual cortex”, J. Neuroscience 2019 https://pubmed.ncbi.nlm.nih.gov/30705101/ 
  • “Development and long-term integration of MGE-lineage cortical interneurons in the heterochronic environment.” J. Neurophys, 2019 https://pubmed.ncbi.nlm.nih.gov/28356470/ 
  • “Caudal Ganglionic Eminence Precursor Transplants Disperse and Integrate as Lineage-Specific Interneurons but Do Not Induce Cortical Plasticity.” Cell Reports, 2016 https://pubmed.ncbi.nlm.nih.gov/27425623/ 

To apply, please send CV and statement of interest to andrea.hasenstaub@ucsf.edu and stryker@phy.ucsf.edu

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