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Expert Scientist - RNA Engineering

Employer
GSK
Location
Rockville, MD
Salary
Competitive
Closing date
Mar 11, 2021

View more

Discipline
Health Sciences, Drug Development
Organization Type
All Industry, Pharma
Are you energized by a challenging role in biology, where scientific demand is driving team growth? If so, this Expert Scientist role would be a great opportunity to consider.

The Vector Biology group at the US Research and Development Center, GSK Vaccines, is responsible for designing, characterizing and optimizing viral vector platforms for vaccine delivery, with a focus on RNA vaccines.

The goal of this Expert Scientist position will be focused on devising and executing experiments in the areas of RNA vaccine discovery and research with a focus on developing and understanding GSK's mRNA vaccine platform.

The successful candidate should have the demonstrated expertise in molecular biology, vector biology and RNA virology. She/he will be a key member of the diverse team of vaccine scientists, to design, characterize, and select RNA vaccine candidates, dissect their mechanism of action, and support platform technology development

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…
  • Design and generate novel RNA molecules that encode a wide variety of proteins
  • Optimize RNA sequence and structure for enhanced modularity and function
  • Utilize RNA biology and virology expertise and new cutting-edge technologies to design best-in-class RNA vector based vaccines
  • Develop and apply novel processes for mRNA synthesis
  • Guide selection of new vaccine platforms design
  • Determine mechanism of mRNA-based antigen expression, innate immune activation and presentation to the adaptive immune system
  • Provide effective and inspiring leadership with an enterprise mindset, ensuring support to professional development and qualification of staff
  • Possesses strong scientific leadership to enable collaboration with key scientific internal and external stakeholders.
  • Publish in peer reviewed journals
  • Supervise students and junior lab personnel as needed


Why You?

Basic qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Ph.D. degree plus at least 2+ years of experience OR Masters with at least 5+ years of experience in RNA biology, RNA virology, biochemistry or related scientific discipline
  • Experience in molecular and cellular biology, including molecular cloning, RNA design, generation and characterization
  • Experience in molecular biology of RNA, RNA sequence design, RNA folding and structural elements, RNA synthesis and purification
  • Track-record of scientific publications in peer-reviewed journals, with at least 3 first author research manuscripts
  • Hands-on experience in current technologies supporting the interrogation of nucleic acid research


Preferred qualifications:

If you have the following characteristics, it would be a plus: ​
  • Skills in statistical analysis
  • Experience with RNA based vaccines or therapeutics
  • Experience in RNA virology, especially alphaviruses, and viral engineering for viral-vector based vaccine design and/or mRNA based vaccines or therapeutics
  • Experience on RNA structure and/or knowledge of innate immune responses
  • Background in eukaryotic post-transcriptional gene expression mechanisms is a plus
  • Excellent communication and presentation skills


Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk, governance and control, managing ambiguity and paradox.
  • Managing individual performance.
  • Creating a performance culture and driving results, prioritization, execution, delivering performance.
  • Setting strategic direction and leading on-going organizational transformation.
  • Building a resilient organization.
  • Building strong relationships and collaboration in service of common goals, engaging the organization and building trusted external networks for mutual benefit.
  • Managing P&L and capital allocation.


If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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