Mass Spectrometrist

Groton, Connecticut
February 25 2021
Other, Other
Position Type
Full Time
Organization Type
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

An opening is available for a Mass Spectrometrist Senior Scientist in the Structure Elucidation Group, Pharmaceutical Sciences Small Molecule Division of Pfizer Worldwide Research and Development in Groton, CT. The Structure Elucidation Group supports all areas of pharmaceutical drug development. It is responsible for the characterization of drug candidates, formulations, excipients, degradation products and impurities. The group interacts with technology and project groups throughout Pfizer. The position will be heavily focused on all aspects of the structure elucidation and characterization of small organic molecules.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It
  • Elucidate chemical structures and solve scientific questions for small molecules of pharmaceutical interest using high resolution mass spectrometry tools.
  • Work within a team of disparate scientific disciplines as a subject matter expert (e.g., working closely with mass spectrometrists, NMR spectroscopists, purification scientists, analytical and organic chemists, etc.).
  • The individual will be expected to provide strong technical and strategic input to ensure efficient and timely execution of deliverables.
  • Investigate innovative scientific approaches to all aspects of mass spectrometry support for pharmaceutical development.
  • Utilize digital tools to enhance workflows.
  • Write technical documents.
  • Publish and present externally.


  • The successful candidate will have a B.S./M.S. degree with 5+ years of mass spectrometry experience or a Ph.D. degree in chemistry or equivalent with expertise in small molecule mass spectrometry with 0-5 years of experience

  • Experience in structural elucidation of small molecules using mass spectrometry.
  • Knowledge of various ionization sources, mass analyzers and detectors required for structure elucidation of both API and complex drug product formulations.
  • Working knowledge of ionization induced fragmentation mechanisms and ability to utilize MS tools to propose solutions to a variety of structure/degradation questions.
  • Fundamental understanding of organic chemistry.
  • A strong understanding of the theory and application of mass spectrometry.
  • Experience with Thermo and Bruker systems.
  • Strong communication skills and a demonstrated ability to carry out independent research are required.
  • S trong interest and motivation to learn new technologies and concepts is expected.
  • Experience with MS processing software (Xcalibur, DataAnalysis, Masslynx, ACD etc.).

  • Ability to adhere to safe laboratory practices.

Other Job Details:
  • Last Date to Apply for Job: March 12, 2021
  • Eligible for Relocation Package: YES
  • Eligible for Employee Referral Bonus: YES

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development