Skip to main content

This job has expired

Associate Scientist

Employer
Pfizer
Location
Andover, Massachusetts
Salary
Competitive
Closing date
Mar 3, 2021

View more

Discipline
Health Sciences, Drug Development
Position Type
Full Time
Organization Type
All Industry, Pharma
Role Summary:

The purpose of the Associate Scientist position is to provide the planning and execution of experiments to design and optimize manufacturing processes for biopharmaceuticals. The successful candidate will have a Bachelor's degree in Chemical Engineering, Chemistry/Biochemistry, or Biology, and have a working knowledge of biochemistry and related analytical chemistries, preferably in chromatography, centrifugation, precipitation, and filtration design principles. This position requires the design and execution of experiments using the aforementioned technologies and the ability to evaluate and clearly reporting the results to laboratory colleagues and other affected functional areas.

Role Responsibilities:

The successful Associate Scientist applicant will have experience in laboratory research, and a desire to continue in a laboratory-focused role. This position will join a larger team of scientists across multiple sites focused on developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials. The Associate Scientist will be responsible for working with fellow scientists to develop robust, efficient, scalable strategies for improving downstream process performance. The job function requires judgment and innovation to achieve a solution within standard practices and procedures. Responsibilities will include conducting experiments, tests, analyses as part of a variety of research and development activities, e.g., small-scale studies, pilot plant and manufacturing downstream purification studies. The Associate Scientist will be expected to summarize, evaluate the study results, develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes. This position will support process validation, quality by design, regulatory approaches, and innovative research. This position will be expected to prepare internally reviewed technical reports, and make oral presentations to scientists and management. The successful candidate must be able to endorse change to business infrastructure to ensure pipeline, legacy and technology success.

Qualification:
  • BS degree in a biological or engineering discipline (Biotechnology, Chemistry/Biochemistry, Chemical/Biochemical Engineering, or equivalent).
  • 0-2 years experience in laboratory research required, preferably in recombinant protein/biomolecule purification process development, technology transfer and/or bioprocess manufacturing.
  • Demonstrated ability to drive for results and generate innovative solutions with minimum supervision.
  • Applicants should be self-motivated, organized, capable of working independently, and in a collaborative environment.
  • The successful candidate will possess strong oral and written communication skills.
  • Experience in transferring Biotherapeutic processes to pilot plants or manufacturing organizations, and knowledge of data acquisition and controls systems in these environments is a plus.
  • A good understanding of protein chemistry, protein analytics, and bioprocess technology is required.
  • Strong analytical and computer skills are desirable. Sound understanding of statistical experimental design and analysis is a benefit.


Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As an Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be responsible for the design and execution of experiments using a variety of cell culture technologies and working with other colleagues to execute complex studies and to perform data analysis. You will work with a matrix team of scientists to enable the manufacture and delivery of life-changing gene therapy medicine to patients.

Your strong foundation in general scientific practice, its principles and concepts will help in meeting critical deadlines. You will be relied on as a technical contributor to assess the assigned tasks and make decisions that involve direct application of your knowledge. You will help Pfizer develop new and improved processes used in the research and development of our drugs. Your innovative mindset will help us develop economical, efficient and safe chemical manufacture of experimental and active drug materials.

It is your hard work and focus that will make Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It
  • Exercise and build basic team effectiveness skills (e.g., commitment, feedback, consensus management) within immediate work group.
  • Contribute to a range of highly innovative analytical ideas to support global process development projects.
  • Develop a safety test plan suitable for the potential process hazards and perform all required process safety testing.
  • Provide analytical support in technical transfer and troubleshooting of commercial Active Pharmaceutical Ingredients (API) processes to relevant API sites and global technical groups.
  • Apply enzyme biochemistry principles to develop and adapt innovative technologies.
  • Summarize, evaluate the study results, develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes.
  • Oversee process validation studies carried out at manufacturing scale.
  • Prepare internally reviewed technical reports, and make oral presentations to scientists and management.
  • Investigate new technologies and analytical approaches to bring added value to Pfizer Global Supply.
  • Document results and assist with interpretation of findings.
  • Work in a collaborative environment of a multi-disciplinary project team.
  • Bachelor's Degree
  • Practical experience in a range of analytical techniques.
  • Strong working knowledge of synthetic organic chemistry principles.
  • Demonstrated high performance in synthetic organic chemistry experimentation.
  • Self-motivated, organized, capable of working independently, and in a collaborative environment.
  • Excellent oral and written communication skills with ability to communicate results through written reports, publications and related documentation.
  • Strong analytical and computer skills.


Nice-to-Have

  • Experience in a Biological/Viral Pilot Plant or Commercial Manufacturing setting is desired.
  • Familiarity of reaction optimization protocols for various enzyme parameters.


PHYSICAL/MENTAL REQUIREMENTS
  • This position will require standing for long periods of time in a laboratory setting.
  • Occasional lifting of equipment may be required


NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIRE

MENTS
  • Occasional travel to vendor, Pfizer or contract manufacturing/research sites may be required.


Other Job Details:
  • Last Date to Apply for Job: March 2, 2021
  • Eligible for Employee Referral Bonus: YES


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

#LI-PFE

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert