Senior Associate Scientist Early Bioprocess Development, Vaccine Development

Pearl River, New York
February 22 2021
Position Type
Full Time
Organization Type

The Senior Associate Scientist will be responsible for working with fellow scientists to purify a variety of macromolecules including; mRNA, DNA, antibodies, recombinant proteins, and polysaccharides. The job function requires judgment and innovation to achieve a solution within standard practices and procedures. Responsibilities will include conducting experiments, tests, and analysis as part of a variety of research and development activities. The Senior Associate Scientist will be expected to summarize, evaluate the study results, develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes.

It is also expected that the incumbent will perform analysis / characterization of isolated macromolecules with various bioanalytical methodologies. Careful documentation of work and presentation of data is required.

Conducts all activities and makes decisions that are in accordance with Company policies & SOPs, Pfizer Values, & global regulatory guidelines (including cGMP/cGLP/cGCP), environmental guidelines, as appropriate, etc.

  • Develop, optimize, and scale-up recovery/purification processes for isolation of mRNA, proteins and polysaccharides.
  • Collaborate with colleagues within Vaccine Research and Development organization including Bioprocess Fermentation, Analytical, and Formulation Development groups.
  • Present problems and propose solutions in discussions with group members.
  • Plan and prioritize related recovery / purification activities.
  • Independently analyze, interpret, and provide conclusion and present experimental data.
  • Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review. Utilize new technologies and establish those technologies to improve purification / recovery capabilities of process development group.
  • Where applicable, perform job responsibilities in compliance with GLP and all other regulatory agency requirements.
  • Satisfactorily complete all GLP and safety training in compliance with departmental requirements and follow appropriate safety practices in the workplace.
  • Perform timely notebook entries and review for completed experiments.
  • Perform other duties as assigned.

  • The incumbent will interact with Bioprocess Fermentation, Analytical, and Formulation Development groups for support of process development, sample analysis, and formulation activities.


Financial Accountability
  • The incumbent advises the supervisor of the equipment and consumables required to accomplish the work.

  • BS degree with 3-5 years relevant experience, or a MS degree with 0-2 years relevant experience.
  • A strong background in protein biochemistry, biophysics, and separation techniques is essential. Hands on experience with protein purification is preferred. Hands on experience with RNA purification is highly desired.
  • Experience of FPLC and TFF systems is highly preferred.
  • Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable. Strong verbal and written communication skills are required.

  • Knowledge and ability to independently design, plan, and execute purification / recovery activities. Proficiency and ability to utilize various techniques such as HPLC, UV-Vis, CD, and DLS is preferred but not required.
  • Independently analyze and provide conclusions regarding experimental data generated.

Other Job Details:
  • Last Date to Apply for Job: February 26, 2021
  • Eligible for Employee Referral Bonus: YES


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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