Principal Scientist, Immune Oncology

NGM Biopharmaceuticals, Inc. is a biopharmaceutical company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases.  Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to build a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine that has a track record of generating one new IND candidate per year.  NGM’s current pipeline of clinical-stage programs consists of five drug candidates targeting liver and metabolic diseases, retinal diseases and cancer.  The most advanced drug candidate, aldafermin (NGM282), is in Phase 2b clinical studies in non-alcoholic steatohepatitis (NASH) and is wholly-owned by NGM.  Another drug candidate, NGM621, is in a Phase 2 study in geographic atrophy (GA) secondary to age-related macular degeneration (AMD).  NGM’s strategic collaboration with Merck, with a current term running to March 2022, provides us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates. 

NGM has built a world class Oncology group and a robust pipeline, and is excited to hire a Principal Scientist/Group Leader to help us develop new drug programs. This position is ideal for a seasoned researcher/independent investigator with substantive industry or tenure-track experience in oncology.

Responsibilities

• Provide foundational expertise in Immunology and Cancer Biology, and serve as an internal thought-leader and strategist in oncology
• Lead a group of scientists to discover, validate, and develop targets from concept to IND candidate
• Design and execute experiments in human and in vitro models
• Evaluate, synthesize, and incorporate data from the broader field to ensure that NGM Oncology research is cutting edge
• Present research on behalf of NGM Oncology to external collaborators, our Scientific Advisory Board, Board of Directors, and investors
• Author publications, patents, and investigational new drug applications as required
• Mentor and coach scientists and junior team members to design experiments and execute on research programs
• Facilitate scientific decision-making meetings for both internal and external stakeholders

Qualifications

• Ph.D. with a Post-Doc and 6+ years of industry experience in Immuno-Oncology or Cancer Biology, or equivalent experience as Junior Faculty on the tenure track with levels of increasing responsibility as a group leader and an outstanding publication record
• Experience leading research teams, directly managing and mentoring scientists, as well as junior researchers
• Demonstrated scientific productivity as evidenced by a strong record of advancing drug development candidates, or by a thorough record of high-impact publications, presentations, and patents
• Outstanding written, presentation, and oral communication skills

NGM offers a creative, collaborative, highly challenging scientific environment, along with a strong compensation package that includes salary, stock options, 401(k) and a comprehensive benefits package.