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Senior Associate Scientist, BioProPuriRecv

Employer
Pfizer
Location
Andover, Massachusetts
Salary
Competitive
Closing date
Feb 25, 2021

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Discipline
Health Sciences, Drug Development
Position Type
Full Time
Organization Type
All Industry, Pharma
ROLE SUMMARY

The purpose of the Senior Associate Scientist position is to provide the planning and execution of experiments designed to aid in defining manufacturing processes for biopharmaceuticals. The successful candidate will have a working knowledge of biochemistry, and related analytical chemistries, chromatography, centrifugation, precipitation, and filtration design principles. This position requires the design and execution of experiments using these technologies and the ability to evaluate and clearly reporting the results to laboratory colleagues and other affected functional areas.

ROLE RESPONSIBILITIES

The successful Senior Associate Scientist applicant will have experience in laboratory research, and a desire to continue in a laboratory-focused role. This position will join a larger team of scientists across multiple sites focused on developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials. The Senior Associate Scientist will be responsible for working with fellow scientists to develop robust, efficient, scalable strategies for improving process performance. Responsibilities will include small-scale studies, and pilot plant and manufacturing downstream purification studies. Based on the analyses of these studies, this position will be expected to develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes. This position will support process validation, quality by design, regulatory approaches, and quality systems. This position will be expected to prepare internally reviewed technical reports, make oral presentations to scientists and management, and publish externally. The Senior Associate Scientist will be responsible for executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes. The successful candidate must be able to endorse change to business infrastructure to ensure pipeline, legacy and technology success.

BASIC QUALIFICATIONS
  • BS (3+ years experience) or MS degree in a biological or engineering discipline (Biotechnology, Biochemistry, Chemical/Biochemical Engineering, or equivalent)
  • Applicants should be bright, organized, self-motivated, and capable of working independently, and in a collaborative environment.
  • The successful candidate will possess strong oral and written communication skills.


PREFERRED QUALIFICATIONS
  • 0-2 years experience in recombinant protein/biomolecule purification process development, technology transfer and/or bioprocess manufacturing.
  • Demonstrated ability to drive for results and generate innovative research
  • Diverse work experience recovering recombinant proteins/biomolecules from mammalian and microbial/yeast cultures.
  • Experience transferring Biotherapeutic processes to pilot plants or manufacturing organizations, and knowledge of data acquisition and controls systems in these environments is desirable.
  • A good understanding of protein chemistry, protein analytics, and bioprocess technology, including the recent scientific literature, is required. Strong analytical and computer skills.
  • Sound understanding of statistical experimental design and analysis is a benefit. It would be advantageous for the successful candidate to have a strong working knowledge of the drug development process for progression of a biological candidate.


PHYSICAL/MENTAL REQUIREMENTS
  • This position will require standing for long periods of time in a laboratory setting.
  • Long periods of sitting at computer work station are required.
  • Occasional lifting of equipment may be required. Occasional travel to vendor worksites may be required.


Other Job Details:
  • Last Date to Apply for Job: March 3, 2021
  • Eligible for Employee Referral Bonus: YES


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Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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