Postdoctoral Associate

Employer
Medical College of Wisconsin
Location
Wisconsin (US)
Salary
Commensurate with experience
Posted
February 17 2021
Position Type
Contract
Organization Type
Academia
Job Type
Postdoc

Job overview

We are currently seeking a highly motivated and creative postdoctoral associate, focused on serotonin drug screening and profiling signaling pathways at G protein-coupled receptors (GPCRs). The successful candidate will be employed on a full-time, fixed term contract for 2 years.

Aims of this project are to assist in analyzing novel serotonergic agents with therapeutic potential.

Qualifications

  • Candidates with a doctorate in either pharmacology, biochemistry, cell biology, and/or medicinal chemistry, who are capable of independent work in a laboratory setting
  • Candidates should have strong backgrounds in compound screening utilizing high-throughput technology (ie 384 well format), cell culture and aseptic technique, screening assay operation and biochemical assay design
  • Candidates are also strongly recommended to have molecular pharmacology experience with mastery of molecular biology techniques
  • Candidates with a strong track record of publications in the fields of biochemistry, pharmacology and/or neuroscience are strongly encouraged to apply

Requirements

  • Independently design and execute high-throughput screening experiments relevant to new compounds using existing GPCR protocols and methodologies
  • Maintain an organized and up-to-date laboratory notebook and computer, complete with methodologies, data, and interpretation of results
  • Maintain and work with existing cell lines (freeze/thaw, subculturing). Organization of compound libraries and compound stocks
  • Perform molecular biology techniques to make new DNA constructs and maintain construct libraries
  • Communicate weekly with principal investigator about methodologies and data analysis
  • Participate in regular lab meetings with principal investigator and research staff and evaluate/interpret the validity of data, novel methodologies, and lab procedures
  • Interact and participate in departmental meetings, including relevant seminars and journal clubs