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Investigator, Mass Spectrometry

Employer
GSK
Location
Collegeville, PA
Salary
Competitive
Closing date
Feb 4, 2021

View more

Discipline
Other, Other
Job Type
Group Leader/Principal Investigator
Organization Type
All Industry, Pharma
Are you looking for a challenging opportunity that allows you to leverage your technical expertise in Mass Spectrometry? If so, this Investigator, Mass Spectrometry role could be an exciting opportunity to explore.

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…
  • Plan, design and execute work/experimental programmes to further the course of Discovery and Development Projects / programmes and enable key decisions, using mass spectrometry expertise (both LC-MS and/or GC-MS qualitative and quantitative).
  • Ensure appropriate use of mass spectrometry to define control strategies for New Chemical Entities (NCE's).
  • Explore and implement innovative research areas and/or apply innovative solutions to project problems.
  • Operational knowledge of laboratory/plant equipment.
  • Plan and communicate effectively and identify technical or resource issues and propose/discuss solutions and strategies with team members and more senior staff.
  • Demonstrate a high level of problem solving capability and ability to identify and troubleshoot unexpected results or findings.
  • Contribute to regulatory dossiers and author/review expert reports.
  • Comply with the requirements of Quality, Safety and GSK policies and procedures and ensure that GSK intellectual property is protected.
  • Ability to contribute to and effectively work within matrix teams and with colleagues in other divisions and colleagues in same divisions e.g. NMR.
  • Self-motivated flexible approach with good organisational skills and ability to communicate in a scientific manner.
  • Working knowledge of GxP requirements, SOPs and policies.
  • Appropriate knowledge of regulatory requirements as applied to the drug development process.


Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:
  • PhD in Analytical Chemistry, in a mass spectrometry related discipline
  • OR MS in chemistry or related field with +5 years' experience in organic chemistry
  • Experience in structural identification of small molecules using Mass Spectrometry


Preferred Qualifications:

If you have the following characteristics, it would be a plus:
  • Knowledge of state-of-the-art high resolution LC-MS and GC-MS instrumentation (e.g. Q-Tof and Orbitrap) in order to provide key information for projects at all stages of pharmaceutical development (from early phase development to marketed product support).
  • Proven track record of structural characterisation/elucidation work of small molecules (i.e., metabolites, impurities, degradants, etc.) using MS and tandem MS techniques
  • Proven track record of innovation in the field of mass spectrometry supported by publications and presentations at international conferences
  • Proven track record of development of novel LC-MS and/or GC-MS methodology
  • Experience in analysis of biomolecules by mass spectrometry is an advantage
  • Experience in developing quantitative analysis methods using mass spectrometric techniques
  • Experience in regulated GxP laboratory is a plus
  • Strong communication and interpersonal skills
  • Knowledge of spectroscopic techniques other than mass spectrometry would be an advantage, e.g. NMR, vibrational spectroscopy
  • Experience in troubleshooting MS methods


Please use the cover letter to highlight how you meet the competencies for the role. Your cover letter along with your CV will be used to assess your application. Thanks for your interest in this opportunity.

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness


If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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