Scientist - Bioinformatics

Rockville, MD
December 08 2020
Organization Type
Are you looking for a role in bioinformatics where you can impact scientific contributions that advance drug discovery? If so, this role could be an ideal opportunity to explore.

The Molecular Biology and Systems Serology function at the US Research and Development Center, GSK Vaccines, is responsible for the application of molecular biology and microbiology to identify antigen compositions, enabling of vector platforms for vaccine delivery, application of cell biology and systems serology to define vaccine potency and mechanism of action, and establishment of molecular biology technical capacity for vaccine development. The mission of the Laboratory of Molecular Analytics is to provide assay and analytical support to all vaccine projects in the US Research and Development Center, using advanced high-throughput technology and techniques.

We are looking for a highly motivated scientist, with proven genomics data analysis experience, to join our diverse preclinical research and development team working on RNA vaccines.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
  • Design, develop, and implement next-generation sequencing (NGS) data analysis pipelines for the characterization of RNA and DNA molecules of interest for vaccine research and development, and their mechanism of action.
  • Perform bioinformatics analysis of wide range of experiments/technical studies/tasks, testing sequence identity and gene expression profiles using single-molecule sequencing, RNA-Seq, and single cell analysis.
  • Analyze, interpret and record experimental results and presents them in written/oral communications.
  • Develop and execute new bioinformatics tools and proactively incorporate new analysis techniques into practice with minimal supervision.
  • Collaborate with bench scientists and bioinformaticians throughout the organization to support NGS activities.
  • Perform complex data management tasks with minimal supervision.
  • Lead vaccine development-related scientific investigations and publishes the work in scientific journals and patent filings.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:
  • PhD in Bioinformatics, Computational Biology, or Computer Science with 0+ years of experience OR Master's Degree with 3+ years' experience working in pharmaceutical/biotechnology industry, academic or government institutes.
  • Proficiency in UNIX operating system and computer programming languages such as: Bash, awk, C, C++, Perl, Python, R, and JAVA.
  • Proficiency in implementation of industry standard bioinformatics tools.
  • Proficiency in writing scripts and performing programming to customize and optimize current software suites and to retrieve data from external bioinformatics databases.
  • Experience with statistics supporting differential gene expression and gene set analysis.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:
  • Ability to develop web-based tools for data visualization.
  • Experience in systems biology, modeling, and analysis of high-dimensional data sets.
  • Experience in Machine Learning.
  • Familiarity with Immunology concepts.
  • Demonstrate a detailed knowledge of Genomics.
  • Effective written and oral communication skills as well as presentation skills. Fluency in English.
  • Detail oriented; possess problem solving skills and the ability to handle multiple tasks.
  • Able to efficiently manage uncertainty, changes in priority and timeline restrictions.
  • Demonstrate hands-on experience in NGS data analysis of RNA-Seq, 3rd generation sequencing (Pacific Biosciences, and Oxford Nanopore) and single-cell analysis.

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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