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QC Analyst - Molecular Biology

Employer
Pfizer
Location
North Carolina - Morrisville, North Carolina
Salary
Competitive
Closing date
Jan 26, 2021

View more

Discipline
Life Sciences, Biology, Molecular Biology
Position Type
Full Time
Organization Type
All Industry, Pharma
ROLE SUMMARY

The successful applicant will have significant experience in viral vector quality control related to molecular biology and Next-Gen Sequencing. The position is heavily focused on benchwork and sequence analysis, the applicant should have a desire to continue in a laboratory focused role. This position will join a larger team of scientists across multiple sites focused on advancing Pfizer's gene therapy platform. The scientist will be a key member of the Quality Control (QC) team that will support the production of viral constructs through quality control assays including: qPCR, Next-Gen sequencing, protein analytics (CE-SDS, silver staining, capsid screening), endotoxin testing, and DNA content assessment. The scientist will be responsible for working with fellow colleagues to perform standard QC assays in a reproducible and timely fashion.

ROLE RESPONSIBILITIES
  • Pay close attention to experimental details, generate robust and consistent results. Manages time and workload efficiently.
  • Takes the initiative to solve scientific problems and contribute to their resolution. Ability to work in a fast-paced team environment with changing priorities. Works under minimal supervision.
  • Evaluate data and provide clear reports that can be shared and transferred to and from cross-functional teams.
  • Support laboratory activities by monitoring lab equipment and maintaining a clean and safe working environment.


BASIC QUALIFICATIONS
  • Bachelor's degree with 6 + years of experience or Masters degree with 5 years of experience with a degree in a biological discipline (Molecular Biology, Bioinformatics, Biotechnology, Virology, or equivalent).
  • Demonstrated capabilities in molecular techniques: qPCR, protein analysis, DNA purification/analysis.
  • Experience with aseptic technique, strong quantitative bench skills, experience in quality control assays for viral production, purification and quantification.
  • Able and willing to learn new procedures and techniques.
  • Applicants should be self-motivated, organized, capable of working independently and in a collaborative environment.
  • Ability to prioritize and multi-task concurrent project demands, while maintaining exceptional attention to detail as well as organization.
  • Strong computer skills in Microsoft Office required e.g. MS Word and MS Excel.


PREFERRED QUALIFICATIONS
  • Experience with QC of viral vectors for gene therapy.
  • Experience with bioinformatic processes to evaluate next-generation sequencing data, sequencing analysis software, and large dataset processing
  • Experience with CE-SDS and cIEF.
  • Experience with ddPCR.
  • Experience with denaturing gels for DNA analysis.
  • Experience with plasmid production and analysis, and experience with VNTI or related program.
  • Experience with plasmid production and analysis, and experience with VNTI or related program.
  • General knowledge of AAV.
  • Able to communicate effectively to all levels of the organization.


Other Job Details:
  • Last Date to Apply for Job: January 25, 2021
  • Eligible for Employee Referral Bonus
  • Relocation support available

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Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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