Senior Scientist - Cell Biologist

Collegeville, PA
December 03 2020
Organization Type
Job Type
Senior Scientist
This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following…

We are seeking a highly motivated Senior Scientist to work on new treatments to address the threat of infectious diseases by joining our growing Infectious Diseases Research Unit (ID RU) at Upper Providence, PA. The ID RU is one of the 4 Research Units in the R&D organization at GSK and is responsible for the discovery of novel approaches & targets to treat infectious diseases that threaten our health and progressing them to clinical proof of concept studies. The Research Unit has an impactful portfolio of projects in hepatitis B, bacterial infections and viral respiratory infections (including COVID-19) along with collaborations with Vir Biotechnology and 23&Me.

The successful candidate within the Infectious Diseases Research Unit (IDRU) will be responsible for conducting cell and molecular biology experiments to progress drug discovery projects targeting immunulogical mechanisms of infectious diseases. Particular areas of focus include in vitro cell based infection assays using various cell lines, primary human cell lines, and organoid models, and experiments using biochemical and molecular techniques. In addition, the successful candidate may be expected to contribute to the establishment and characterization of target validation studies and mechanistic elucidation of molecules arising from high throughout library screens in the discovery of new anti-infective medicines.

Key accountabilities:
  • Coordinates with Program Leaders/scientists to plan and execute experiments
  • Works collaboratively on aspects of experiments to be performed by other members of the team
  • Contributes to driving the scientific direction
  • Interprets results and designs next logical step of experiments based on interpretation of results
  • Performs complex data management tasks with minimal supervision
  • Prepares detailed oral or written summaries of results with interpretation for projects/programmes; independently writes specific technical sections of internal and external reports
  • Assumes responsibility for posting data, tracking usage of reagents, maintaining updated electronic lab notebook records
  • Assists in publishing, patenting or presenting data as needed
  • Assists in general operation of the biology lab facility

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:
  • BS with 3-5 yrs experience with a background in cell and molecular biology
  • Candidates must have knowledge/experience in cell culture
  • Hands-on technical experience with cellular/molecular biology and immunology assays (e.g. SDS-PAGE analysis, Western blotting, qRT-PCR, PCR, ELISA, transfection, immunofluorescence, flow cytometry).
  • Strong work ethic with desire to carry out independent hypothesis generation and testing
  • Experience with data handling software (e.g. Spotfire, GraphPad, Excel)
  • Candidate must be a highly motivated self-starter, with excellent verbal and written communication skills, and the ability to work effectively individually and in team and matrix environments
  • Prior experience utilizing in vitro primary cell culture and/or immune cellular models.
  • Outstanding written and oral communication skills

Preferred Qualifications:

If you have the following characteristics, it would be a plus:
  • MS degree (1-3 yrs experience) with a background in cell and molecular biology and >2 years experience in industry
  • Experience with preclinical drug discovery
  • Experience in liquid handling equipments/ automation and other technical equipment
  • Experience in in vivo or in vitro work with viral or bacterial infection
  • Experience in immunology and virology

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.


*This is a job description to aide in the job posting, but does not include all job evaluation details.

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