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Scientist (non-PhD), Tumor Immunogenicity

Employer
Pfizer
Location
La Jolla, California
Salary
Competitive
Closing date
Dec 9, 2020

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Discipline
Life Sciences, Immunology, Health Sciences, Drug Development
Position Type
Full Time
Organization Type
All Industry, Pharma
ROLE SUMMARY

Pfizer Cancer Immunology Discovery (CID) is within the Oncology division of Pfizer Worldwide Research & Development in La Jolla, CA. CID is dedicated to developing new protein and small molecule therapeutics to improve human life by redirecting the immune system against cancer. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics. We are seeking to hire a BS/MS level scientist for the Tumor Immunogenicity CID group.

ROLE RESPONSIBILITIES
  • Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development.
  • Planning and execution of in vivo mouse studies and ex vivo functional assessments, such as multi-color flow cytometry, gene expression analyses, and primary cell culture.
  • Analyze, organize, and present results in small and large group meetings.
  • Read relevant scientific literature to aid in experimental design.
  • Contribute to a dynamic, exciting culture that embraces teamwork and innovation.


BASIC QUALIFICATIONS
  • B.S. degree with 6+ years' experience
  • Experience in the fields of immunology, cell biology, and/or tumor biology.
  • Ability to plan and execute in vitro and/or in vivo/ex vivo experiments with minimal supervision.
  • Expertise in standard immunologic techniques.
  • Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic .


PREFERRED QUALIFICATIONS
  • M.S. degree with 4+ years of experience
  • Technical expertise with immune cell-based functional assays (e.g. activation, differentiation, proliferation, and suppression assays by using monocyte/ macrophages, T-cells, or dendritic cells).
  • Immune phenotyping tumor associated immune cells from primary human tumor samples by flow cytometry.
  • Experience with flow cytometry, qRT-PCR, MSD, Nano string and cytotoxic assays.
  • Experience in CRISPR technology and lentiviral transduction.
  • Experience with various murine tumor and/or infectious disease models.
  • Experience with human PBMC and mammalian cell culture.


Other Job Details
  • Eligible for Employee Referral Bonus: YES


#LI-PFE

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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