Senior Scientific Researcher - In Vitro Human Brain Modeling

Join a Team that Lives to Improve Lives
People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen. 

The following opportunity exists in our South San Francisco, CA headquarters:

SENIOR SCIENTIFIC RESEARCHER - IN VITRO HUMAN BRAIN MODELING

Description
We are seeking an independent and creative researcher for a Senior Scientific Researcher position to support discovery research and drug discovery efforts within the Department of Neuroscience at Genentech.  This is an exciting opportunity to build an in vitro human brain modeling platform to help us understand molecular mechanisms of neurodegenerative disease and pathology. The successful candidate will develop human stem cell-based in vitro models to understand the basic molecular mechanisms of neurodegeneration. The successful candidate will have access to state-of-the-art resources at Genentech and will work in our fast-paced and highly collaborative environment.

Who You Are
Candidates must have a PhD in cell biology, molecular biology, neuroscience or developmental biology or similar degree, with a focus on applications of stem cell technology to neurological disorders. Candidates in both academic or industry settings are encouraged to apply. 

The successful candidate should be fearless and resilient in pursuing novel technologies and methods to generate complex human cellular models. Exceptional productivity needs to be evidenced by high-quality work published in high-impact journals or by contributions to stem cell technology in neuroscience drug discovery.  The successful candidate must be able to thrive in a fast-paced, team-focused, multiple shots-on-goal, and collaborative environment.

Hands-on experience with iPS cell culture, multi-lineage differentiation of CNS cell types, novel differentiation methods such as direct differentiation, complex systems such as brain organoids or co-cultures, and genetic manipulation of such models by CRISPR/Cas9 are required.  Experience in practical applications of stem cell technology to target validation and drug prioritization as well as automation and assay development are desired.

Who We Are
Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and
life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society.  We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work. 

The next step is yours. To apply today, click on the "Apply online" button.

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At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.