Purification Investigator

Collegeville, PA
September 18 2020
Other, Other
Organization Type
GSK is seeking a highly motivated, experienced analytical scientist with demonstrated capability in the purification of small molecule pharmaceuticals to join the US purification team. In this laboratory-based position, the successful candidate will perform analytical analysis, method development and preparative separations of both achiral and chiral compounds utilizing HPLC, LCMS and SFC platforms to advance small molecule drug discovery programs.

The position requires an individual with strong analytical, technical, reporting and personal skills, some experience of team or matrix management and a commitment to further personal development in both technical and leadership areas.

The US Purification Group is a multidisciplinary team that is part of a global Discovery Analytical department. The Purification Group works with project teams to progress the discovery and development of small molecules from hit identification through early development. This position will help to enable the effective partnership of chemistry teams from Medicinal and Development Chemistry with Discovery Analytical.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Function as a technical expert for chromatographic analysis and purification
  • Perform preparative purifications on multi-gram samples
  • Interpret chromatographic data and develop unique chromatographic methods
  • Ability to use multiple chromatographic software
  • Strong desire to learn with multifunctional learning agility
  • Self-motivated
  • Collaborate with colleagues to design purification process
  • Ability to analyze chromatographic data and make decisions for follow up experiments.
  • Maintain and repair analytical and preparative instrumentation as needed.
  • Track work effort
  • Train junior colleagues in chromatographic analysis and purification

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • PhD or MS with 5+ years' experience or BS with 8+ years' experience
  • Hands on experience with analytical method development and preparative chromatography for small molecule chiral and achiral pharmaceutical compounds.
  • Demonstrated technical expertise and working experience with multiple analytical and preparative techniques.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Advanced knowledge of chiral chromatography as demonstrated by presentations, posters and/or publications
  • Background in associated analytical techniques such as mass spectrometry
  • Experience with large scale purifications (>100 G) using both HPLC and SFC
  • Experience training and mentoring junior scientists
  • Ability to work in a matrix environment within and external to the team to solve problems
  • Self-motivated with excellent organizational skills
  • Outstanding verbal and written communication

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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