Pfizer

Senior Scientist, Early Bioprocess Development

Employer
Pfizer
Location
Pearl River, New York
Salary
Competitive
Posted
November 20 2020
Ref
4796067
Position Type
Full Time
Organization Type
Pharma
Job Type
Senior Scientist
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Scientist Early Bioprocess Development , you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be recognized as a technical expert and a scientific contributor. With your deep knowledge of the discipline, you will be an active team member whose decisions impact the project. You will perform qualitative and quantitative analyses of organic, inorganic compounds, or biologics to determine chemical and physical properties during chemical syntheses, fermentation or drug product development process.

You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide team members.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It
  • Apply understanding of carbohydrate chemistry and structures in order to identify key attributes and develop robust assays used to routinely characterize polysaccharides and polysaccharide-protein conjugates including size, potency, free protein and free polysaccharide content upon stability.
  • Propose and develop analytical assays to support process development with respect to drug substance intermediates, monitoring conjugation processes and measuring process residuals.
  • Perform routine and non-routine sample analysis support for in-process, formulation development, and final vaccine candidates.
  • Independently design, plan, and execute assay development, method qualification (per ICH guidelines) and transfer studies.
  • Document experiments, analyze data, and provide conclusions obtained from assay development and sample testing experiments contemporaneously in either an electronic or paper notebook
  • Establish and utilize new technologies, where required, to enhance the characterization and understanding about the vaccines being developed.
  • notebooks and technical reports.


Qualifications

Must-Have
  • PhD in Chemistry, Biochemistry, or a related discipline with at least 2 years of academic, pharmaceutical, or biotechnology experience or an MS plus 7 years of related work experience is required.
  • Experience and proficiency in separation-based analytical techniques (RP-HPLC, SEC-MALS, HPAEC-PAD, and CE) and method qualification following ICH guidelines is essential.
  • Demonstrated technical skills and scientific expertise in analytical method development and troubleshooting.
  • Strong written and verbal communication skills.
  • Strong MS Office skills



Nice-to-Have

  • Experience working in a regulated environment, such as Good Laboratory Practices {part of GxP}.
  • Experience in the pharmaceutical industry space.
  • Experience in separation-based analytical techniques as applied to vaccines.


PHYSICAL/MENTAL REQUIREMENTS
  • Standard laboratory conditions - sitting, standing, primarily lab based.
  • Ability to perform mathematical calculations and ability to perform complex data analysis


NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
  • 40 hours per week


Other Job Details:
  • Last Date to Apply for Job: November 24, 2020
  • Eligible for Relocation Package: YES
  • Eligible for Employee Referral Bonus: YES


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Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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