Pfizer

Scientist-Protein Biochemistry & Viral Vaccine

Employer
Pfizer
Location
Pearl River, New York
Salary
Competitive
Posted
November 16 2020
Ref
4796453
Position Type
Full Time
Organization Type
Pharma
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

Role Summary

The Viral Vaccine group is seeking a non-PhD scientist to join our highly dynamic team in vaccine research and development. The incumbent is responsible for supporting the antigen discovery, antigen optimization, and the assessment of protein quality. The incumbent will assist with protein expression in bacterial and mammalian cell culture and protein purification using various chromatography techniques based on AKTA system. The incumbent will be responsible for maintaining cell lines, supporting protein and antibody biochemical characterization studies, and daily laboratory operations. Work is to be done in a compliant manner according to relevant SOP guidelines and cGLP and/or cGMP guidelines where appropriate. The successful candidate will possess a strong work ethic and be adaptable to a dynamic environment.

Role Responsibilities
  • Support recombinant protein expression, purification, and molecular biology through cell culture expression (bacterial & mammalian), chromatographic protein purification, and a variety of protein analytical techniques.
  • Support constructs preparation through various molecular biology techniques such as Gibson assembly, PCR, DNA preparation.
  • Analyze immune responses to vaccine candidates using techniques that include (but are not limited to) cell culture, neutralization assays, ELISAs, and Octet for antibody characterization.
  • Independently interpret and summarize experimental data. Present experimental results at group meetings.
  • Generate and characterize reagents used to perform necessary assays and support maintenance of laboratory supplies.
  • Maintain laboratory notebooks in compliance with the Pfizer Laboratory Notebook Policy.
  • Performs other duties as assigned.
  • Satisfactorily complete all safety training in conformance with Departmental requirements.
  • Where applicable, performs job responsibilities in compliance with cGMP/GLP and all other regulatory agency requirements.


Qualifications

  • Non-PhD position. Master's degree in Biochemistry with 4+ years of industry research experience, or B.S. with 8-10 years of industry laboratory research experience.
  • Knowledge of protein expression and purification is required. Experience with AKTA system is required.
  • Knowledge of methods in virology and immunology highly preferred.
  • Proficiency with personal computers including Word, Excel or Graphpad Prism, PowerPoint and relevant scientific software is desirable.


PHYSICAL/MENTAL REQUIREMENTS

  • Basic laboratory training in aseptic technique is essential.
  • Ability to work with infectious agents safely.
  • The capacity to work effectively in a highly visible research program with time-constrained milestones.


Other Job Details:
  • Eligible for Employee Referral Bonus: YES


#LI-PFE

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

Similar jobs

Similar jobs