Postdoctoral Research Associate

Collegeville, PA
June 19 2020
Organization Type
Post-Doctoral Research Associate Position

Complex In Vitro Models group at GlaxoSmithKline- Upper Providence


GSK Center for Optical Molecular Imaging at the

Beckman Institute for Advanced Science and Technology,

University of Illinois at Urbana-Champaign

The post-doc would join the Complex In Vitro Models (CIVM) team within the In Vitro In Vivo translation (IVIVT) department in GSK's research organization. CIVMs mission is to improve predictive and translational value of preclinical models. We strive to improve models for mechanism of action, efficacy, safety and metabolism, aiming to assess these in the same systems whenever possible. The CIVM group closely collaborates with the research units, the medicinal science and technology (MST) organization, and other IVIVT groups.

The post-doc will also hold a visiting scholar position in the Biophotonics Imaging Laboratory (BIL) at the Beckman Institute for Advanced Science and Technology on the campus of the University of Illinois at Urbana-Champaign (UIUC). Headed by Prof. Stephen Boppart, the BIL is a dynamic and productive interdisciplinary research and training environment focused on developing novel optical biomedical imaging technologies, translating them into clinical applications, and driving them toward commercialization for improving healthcare.

In 2015, the GSK Center for Optical Molecular Imaging (COMI) was established as an Imaging Centre of Excellence in the BIL at the University of Illinois at Urbana-Champaign . The research focus for the COMI lab is on the development of advanced multimodal optical imaging platforms for driving drug discovery and development. The post-doc will be trained on various optical imaging modalities including SLAM (Simultaneous Label-free Autofluorescence Multi-harmonic Imaging), FLIM (Fluorescence Lifetime Imaging Microscopy) and CRI (Coherent Raman Imaging) techniques, among others, developed in the COMI lab to support various GSK research activities.

GSK is seeking a forward-thinking post-doc for a 3-year term who has an interest in applying the optical imaging technologies developed in the COMI lab towards Complex In Vitro Models in an industrial drug discovery setting. The first part of the 3-year post-doc will be spent at the GSK Upper Providence site learning Complex In Vitro Models and Organoid culture systems that are applicable to drug discovery and the application for using label-free imaging. Once the training is complete, the post-doc will transfer to the COMI lab where the position will offer the opportunity to join the team that is performing proof-of-concept studies using complex in vitro models to develop cutting edge imaging applications in the COMI lab. The post-doc will also support the evaluation and transfer of a prototype deployable SLAM imaging system into a GSK drug discovery unit. Finally, the post-doc's remaining time will be spent embedding the new SLAM technology in GSK at the Upper Providence site, further extending the utility of this technology in a drug discovery setting.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:
  • Recently qualified as a PhD in bioengineering, cellular biology, or related fields, with hands-on experience in optical imaging and microscopy technologies.
  • Experience with pre-clinical research using cell culture, complex in vitro models, spheroids, organoids and/or microphysiological systems.
  • Strong experimental research background in imaging systems for biomedical applications.
  • US Work authorization is required. Sponsorship not available.

Preferred Qualifications:

  • Excellent oral and written communication skills in English.
  • Working experience of image data analysis software (C++, Matlab, Python) is a plus.
  • Willing to learn new technologies and methodologies.
  • Willingness to live and work for extended periods in Philadelphia, PA, and Urbana-Champaign, IL.

This academic position is most suitable for an outgoing and driven individual with leadership goals, and a willingness to take on more independent responsibilities while working as part of an integrated research team of industry scientists and engineers.

Candidates must be eligible to work in the United States. Additional information about the Biophotonics Imaging Laboratory and the Center for Optical Molecular Imaging, including a full list of publications and research areas, can be found at:

Please use the cover letter to highlight how you meet the competencies for the role. Your cover letter along with your CV will be used to assess your application. Thanks for your interest in this opportunity.

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
  • Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.


*This is a job description to aide in the job posting, but does not include all job evaluation details.

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