Postdoctoral Fellow - Metabolism

Duarte, California
January 29 2020
Life Sciences
Position Type
Full Time
Organization Type
Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
NIH-funded postdoctoral research positions are available in the laboratory of Qiong (Annabel) Wang, in the Department of Molecular and Cellular Endocrinology at the City of Hope Beckman Research Institute. The Wang laboratory utilizes the cutting-edge tissue-specific, inducible knockout and lineage tracing mouse models to study the region-specific remodeling of fat tissue, both in physiological and pathological conditions, such as insulin resistance, obesity, and cancer.

Dr. Wang has previously generated the AdipoChaser mice model and tracked adipogenesis during fat tissue development and remodeling (Wang QA, et al. Nature Medicine , 2013). Dr. Wang's other previous research generated a series of inducible knockout mouse models and revealed the surprising diversity of transcriptional signals required at different stages of adipogenesis in vivo (Wang QA, et al. Nature Cell Biology , 2015). The Wang lab is currently working on three projects: 1) Brown fat cell heterogeneity, and how this heterogeneity remodels the thermogenic capacity of brown adipocytes in health and disease (Song A, et al. Journal of Clinical Investigation , 2020). 2) Fat tissue remodeling in the mammary gland in health, metabolic disorders and breast cancer (Wang QA, Song A, et al. Cell Metabolism , 2018). 3) Aging-associated adipogenesis and fat expansion.

We are seeking independent and highly motivated candidates interested in studying the cellular and metabolic mechanisms leading to obesity, diabetes, and cancer. Preferably with expertise in using mouse models to study metabolic diseases.

Basic education, experience and skills required for consideration:
  • Ph.D. and/or M.D.
  • Extensive experience with basic molecular biology skills.
  • Experience in animal models.
  • Experience with immunofluorescence staining and flow cytometry.
  • Excellent written and verbal communication skills.
  • Good problem-solving skills, ability to conduct independent research, ability to work effectively in a team.

Additional Information:
  • For more information on Dr. Wang's research, please click here .
  • To apply, please send your CV and a list of three references to .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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