Postdoctoral Fellow - Lymphoma Research

Location
Duarte, California
Salary
Competitive
Posted
October 19 2020
Ref
10007774
Position Type
Full Time
Organization Type
Healthcare/Hospital
About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary:
We are seeking goal-oriented, highly motivated Postdoctoral Fellow with a passion for science to lead translational immuno-oncology projects.

The main goal of our laboratory is the translational development of immunotherapies for lymphoma. We have a keen interest in understanding how tumor-cell intrinsic mechanisms regulate the endogenous immune response against lymphoma, and how this informs pathways driving response and resistance to immune-based treatments in this disease. We aim to leverage this information to 1) develop novel biomarkers that promote precision-based medicine and 2) discover strategies to further enhance the efficacy of existing immunotherapies.

The lab employs syngeneic and genetically engineered pre-clinical mouse models, as well as patient specimens, in both basic and translational studies of lymphoma. We also use an array of cellular, molecular, and genomic analyses to interrogate questions in several in vitro, in vivo, and bioinformatic studies.

The ideal candidate will have relevant laboratory experience in one more of the following areas of molecular biology and cellular immunology including:
  • Molecular biology techniques:
    • qPCR and Western blots
    • Gene editing via CRISPR/Cas9
    • Experience with -omics platforms (genomics, epigenomics)
  • Cellular immunology techniques including
    • Multi-parameter flow cytometry of mouse and human samples
    • Cell culture of mouse and human cells, including cell lines and primary cells
  • Experience working with lab animals and animal husbandry
    • Syngeneic, transplantable tumor models
    • Familiarity with developing and utilizing genetically engineered mouse models


Qualifications
Basic education, experience and skills required for consideration:
  • Doctorate degree (Ph.D. or M.D.) required
  • A background within molecular biology, cellular immunology and working with lab animals and husbandry is preferred.
  • Basic computational biology skills will also be very valuable but are not mandatory for the position.
Additional Information:
  • For more information on Dr. Godfrey and the Toni Stephenson Lymphoma Center please visit, here
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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