The Paczesny laboratory is seeking highly motivated candidates for a post-doctoral fellowship studying tumor immunology including with hematopoietic cell transplantation to treat myeloid malignancies. The major interests of the lab are discovering and validating new biomarkers and immune cells subsets in tumor immunology, generating new cell-based immunotherapies such as T9IL33 recently published in the Journal of Experimental Medicine and highlighted in the New England Journal of Medicine, as well as developing new small molecules based on discovery of novel targets. In this position, you will have the opportunity to develop and lead projects using several cutting-edge model systems including hematopoietic cell transplantation and novel xenograft in vivo systems, and primary patient samples. You will also gain extensive experience and training in proteomics, hematopoietic cell transplantation biology, and pre-clinical study development.
Successful applicants will have a PhD or MD/PhD with substantial hands-on research experience in immunology and/or cell biology or a related field; a strong publication record in recognized peer-reviewed journals; experience with multicolor flow cytometry and in immunology techniques including ELISAs, flow-based cytokine determination, cellular proliferation and cytotoxicity assays; experience with animal models of bone marrow transplantation is required; be meticulous at planning, executing, and organizing the results for large scale assays. S/he must also be capable of taking initiative, work independently and in a collaborative setting. Excellent written and verbal communication skills are required, as are excellent organizational skills and knowledge of proper scientific record keeping as well as being comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
As this position is funded through the NIH including potential T32, preference will be given to a citizen of the United States, or a non-citizen national, or must have been lawfully admitted for permanent residence and possess an Alien Registration Receipt Card (1-151 or 1-551) or some other verification of legal admission as a permanent resident.
Compensation: Salary according to the NIH scale + excellent benefits
Applicants should apply online and also send a CV including publication list, a research proposal based on the lab interests, and three academic reference letters to:
Sophie Paczesny, MD, PhD
Professor, Microbiology & Immunology & Pediatrics
Chair Dept of Microbiology and Immunology
Medical University of South Carolina
Hollings Cancer Center Immunology co-leader
173 Ashley Ave,
Basic Sciences Building, Ste 203
Charleston, SC 29425