Postdoctoral Fellow - Brenner Laboratory

Location
Duarte, California
Salary
Competitive
Posted
August 19 2020
Ref
10007164rxv_113_1
Discipline
Life Sciences
Position Type
Full Time
Organization Type
Healthcare/Hospital
A postdoctoral fellowship opportunity is immediately available in the laboratory of Dr. Charles Brenner in the Diabetes and Metabolism Research Institute (DMRI) at Beckman Research Institute of City of Hope. The Brenner laboratory examines how nicotinamide adenine dinucleotide (NAD), the central regulator of metabolism, is disturbed by diseases and conditions including cancer, neuropathy, fatty liver, postpartum and viral infection. By identifying alterations in metabolism, we identify ways to sensitize and kill cancer cells, protect damaged nerves, and improve the repair capacity of damaged tissues.

The postdoctoral fellow will dissect mechanisms of transcriptional, post-translational and metabolomic alterations as a function of metabolic stress in order to better model and develop treatments for metabolic diseases and cancer and to support good health in the face of postpartum and viral challenges. Please read more information about the laboratory at http://brennerlab.net .

Applicants are encouraged to carefully read papers downloadable from https://www.brennerlab.net/curriculumvitae/ (eg. paper #129 on postpartum, #135 on glioma, or our recent work on coronavirus https://doi.org/10.1101/2020.04.17.047480 ) . After reading one or more recent papers, applicants should propose a question or an experiment related to work in the Brenner laboratory.

Qualifications
Basic education, experience and skills required for consideration:
  • A PhD or equivalent doctoral degree is required.
  • Creative work as documented by peer reviewed publications.

Preferred education experience and skills:
  • Related training and experience is preferred.

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer, type 1 diabetes, type 2 diabetes and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

City of Hope has one of the most influential type 1 and type 2 diabetes research programs in the world. Our scientists' work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.

To learn more about our exciting research and accomplishments in the field of Diabetes, please visit https://www.cityofhope.org/research/diabetes-metabolism-research-institute