Postdoctoral associate in prostate cancer progression and metastasis

Boston, Massachusetts (US)
Starting at USD 52,704 on NIH payscale for first year postdoc + benefits
October 16 2020
Position Type
Full Time
Organization Type
Job Type

The Shipley Prostate Cancer Center at Boston University School of Medicine seeks a highly motivated postdoctoral fellow to investigate mechanisms of prostate cancer progression and bone metastasis. We are a highly dynamic, interdisciplinary, collaborative group of investigators focused on cancer disparities, and we have pioneered studies of BET bromodomain regulation in cancer. Research focuses on signal transduction in the prostate microenvironment, and new approaches to understand tumor cell aggressiveness and metastasis in cancer patients with co-morbid metabolic disease. We work in a safety net hospital setting, where about half our patients are African American. We are deeply committed to ameliorate the well-known racial disparities for men with prostate cancer.  

Position summary. The successful candidate will work with leading academic clinicians, epidemiologists and basic scientists, and conduct ground breaking, translational research to elucidate understanding of the prostate cancer microenvironment. The successful candidate will conduct pioneering work on the interplay of tumor mutations with microenvironment, metabolism and therapeutics in preclinical models, with the ultimate goal of developing rational treatment hypotheses to be tested in the clinic. This research will deepen understanding of BET bromodomain mechanism and develop novel treatments. The successful candidate will effectively communicate their work by presentation at national/international conferences and publishing their results in premier journals.

Qualifications. Recent PhD or MD PhD graduate in cancer, molecular oncology or related discipline. Experience with molecular biology, biochemistry and cell biology, metabolism, multiparameter flow cytometry, cell culture required. Preferred familiarity with characterization of murine metastasis models. Demonstrated rigor, scientific and technical excellence. Independent, highly self-motivated and innovative. Proven track record in tumor biology, with relevant publications. Excellent written and oral communication skills. Willing to seek out grant funding from external sources in support of their research and to participate in team-based writing of NIH and DoD grant proposals. Outstanding interpersonal skills, strong work ethic and organizational skills. Ability to excel in a goal-oriented, multifaceted and fast-moving team environment, and take advantage of the rich scientific and medical milieu of Greater Boston.

Boston University is an equal opportunity employer and gives consideration for employment to qualified applicants without regard to race, color, religion, sex, age, national origin, physical or mental disability, sexual orientation, gender identity, genetic information, military service, or veteran status or any other characteristic protected by law.

To apply for this position please send a cover letter and CV to Dr. Gerald V Denis.

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