Postdoctoral Position in Intestinal Epithelial Biology and Inflammation

Postdoctoral position in intestinal epithelial biology and inflammation

We have an immediate opening for a Postdoctoral Fellow position in the Dr. Andrei Ivanov Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and interests in studying epithelial barriers, intercellular junctions, cell migration and cytoskeletal remodeling are encouraged to apply.

A highly motivated candidate will join a productive research team to participate in NIH funded projects focusing on the roles of the actin cytoskeleton and myosin motors in disassembly and reformation of tight and adherens junctions and wound healing in the intestinal epithelium during mucosal inflammation, epithelial restitution and colonic tumorigenesis. The candidate should have a publication record demonstrating on-hand molecular biology and cell biology expertise.

Familiarity with epithelial cell culture, Western blotting, and RNA based methods (quantitative PCR and reporter assays), subcloning between different vectors, lenti- retro- and adenoviral systems for cDNA and shRNA delivery is essential. Preference will be given to candidates with previous experience in CRISPR/Cas9-dependent gene editing, confocal microscopy/ image analysis or animal models of gut inflammation. Dedication, critical thinking and ability to work independently are essential. The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript writing and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Please e-mail a cover letter and CV, as well as contact information for 3 references to: Dr. Andrei Ivanov, Department of Inflammation and Immunity; Lerner Research Institute of Cleveland Clinic. E-mail: ivanova2@ccf.org; Phone: (216) 444-5620.