Post Doctoral Position in HIV-1 (and SARS-CoV-2) host-virus interactions, latency and therapeutics

Albert Einstein College of Medicine
Bronx, New York
October 07 2020
Life Sciences, Genetics
Position Type
Full Time
Organization Type

Kalpana Laboratory in the Department of Genetics at the Albert Einstein College of Medicine is seeking to fill a post-doctoral position immediately. Highly motivated PhDs are needed to take part in exciting HIV/AIDS projects.

Kalpana laboratory is investigating host-virus interactions of HIV-1 and the mechanism of persistence and latency. One focus is to study interaction between integrase and INI1/SMARCB1. Solving the structure of INI1/SMARCB1 integrase-binding domain has shed exciting and novel insights about the biology of this interaction. These studies have revealed unprecedented RNA mimicry of INI1/SMARCB1 and led to the development of novel anti-HIV-1 therapeutic strategies. Furthermore, Kalpana laboratory is using single-cell and single-molecule RNA-FISH and single cell RNA-seq to investigate HIV-1 latency and the role of INI1/SMARCB1 on HIV-1 transcriptional and post-transcription events. These techniques are now being extended to the study of SARS-CoV2. The individuals to be appointed will have the opportunity to spearhead these exciting projects designed to unravel the molecular mechanisms of HIV and SARS CoV-2 replication using molecular biology, Biochemistry, Virology, structural biology and cell biology approaches.

Also, please note that NY state has one of the lowest COVID-19 positivity rating!

Please email Dr. Ganjam V. Kalpana

The candidates should have a PhD in Virology, Molecular Biology, Cell Biology, Biochemistry or a closely related field. Applicants with additional qualifications in biochemical and genetic techniques, CRISPR/Cas9 technology are also encouraged to apply.

The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Einstein seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence, and the communities we serve.

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