Postdoctoral Fellow position in neuroimmune regulation of chronic pain

The Laboratories of Neuroimmunology consist of the research teams of five collaborating Principal Investigators who aim at understanding chronic pain, cognitive deficits and fatigue in response to cancer treatment.

We are seeking an enthusiastic Postdoctoral Researcher to study how microglia in the prefrontal cortex and mesolimbic reward circuitry contribute to affective disturbances in the context of chronic pain. Investigations will be performed using transgenic mice and models of neuropathic pain. Experience in working with rodents and a background in pain or immunology is preferred. The position is extramurally funded and is available immediately. We highly value innovation, learning, hard work, creativity and an interactive, respectful and fun atmosphere. The post-doctoral fellow will work under direct supervision of the Principal Investigator on this funded project. 

If you are interested in helping to understand the molecular and cellular mechanisms of pain and developing novel interventions to help improve the quality of life for people suffering from chronic pain in an internationally-renowned, well-funded group of scientists using a highly integrated and interdisciplinary approach in the number one cancer center in the USA, we are the perfect environment for you!

ESSENTIAL FUNCTIONS

1. Research Activity  
• Live cell imaging
• Luciferase assays and immunoassays
• CRISPR/Cas9 gene editing in vitro and in vivo
• Nerve injury surgery

• Transgenic mouse models
• Intrathecal and stereotaxic drug treatments in vivo
• Behavioral assays of pain and affective disturbance in mice
• Collect and process ex vivo biological samples including brain and spinal cord 
• Immunohistochemistry and microscopy studies on cells and nervous system tissues
• Western blotting and qPCR
• Present results in departmental and national meetings
• Prepare and write manuscripts for publication. 

2. Interpersonal Skills, Communication, Learning Skills
• Strong written and oral communication skills 
• Communication with faculty and staff within and outside the laboratory.
• Ability to work with others in a highly collaborative manner.
• Good problem-solving abilities.

3. Other
• Responsible for monitoring laboratory equipment and implementing safety procedures.
• Strong interest in basic and translational research
• Supervision of 1-2 research assistants 


For further information you should contact Birute Ziemiene (bziemiene@mdanderson.org)