Biologics Development Scientist

Houston, Texas
September 15 2020
Organization Type
The mission of The University of Texas M. D. Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

Therapeutics Discovery and Development

MD Anderson Cancer Center (MDACC), the largest research-based Cancer Center in the nation, is taking a unique approach in the battle against cancer. It is well-known that MDACC is home to an esteemed academic faculty that cover all aspects of cancer research, publish prolifically in leading journals and present extensively at all major conferences. In addition MD Anderson boasts a vast oncology clinic that runs more clinical trials than any other institution and has created unparalleled capabilities is cell therapy trials. In between the basic science and the translation, MDACC has created a powerful engine driving the future of new targeted, immune- and cell-based therapies: The Therapeutics Discovery and Development (TDD) Division. TDD eliminates the bottlenecks that hamper traditional drug discovery, with a multidisciplinary team of dedicated researchers, doctors, drug developers and scientific experts working together to develop small-molecule drugs, biologics and cellular therapies. Our unique structure and collaborative approach allows the team to work with agility, bringing novel medicines from concept to clinic quickly and efficiently - all under the same roof.

Biologics Product Development

Biologics, be it monoclonal antibodies (mAbs) or cell therapies are complex therapeutics that are revolutionizing the treatment of cancer and yet are difficult to robustly develop and manufacture. To unlock the potential of these modalities MDACC is investing in Biologics Development capabilities within TDD accelerate the results we have already achieved, with multiple programs currently in clinical development. The goal will be to develop industrial biologics with a commercial horizon within the innovative environment of an academic cancer center. The group will be a composite of industry veterans who are interested in applying their experience to develop innovative therapeutics and see them impact patients, as well as academics looking to turn science into products. We work in a fast-paced, milestone-driven environment with a focus on team science and interdisciplinary research. Our unique approach has created a biotech-like engine within the walls of the nation's leading cancer center to bring life-saving medicines to our patients more quickly and effectively.

Scientist, Cell Therapy Process Development

The Scientist, cell therapy Process Development is a key talent reporting to the Associate Director cell therapy Process Development. MDA is the leader in clinical trials for cell therapies, including the lead site for Kymriah. These clinical capabilities are matched by a faculty that is pressing the boundaries of new cell therapy modalities. In order to advance these promising concepts to and through the clinic, we are investing in new internal process development and manufacturing capabilities.

The successful candidate will lead the transformation and industrialization of cell therapy manufacturing processes with state of the art technologies. The incumbent will be a key member of various project teams representing process development function. The incumbent will be expected to work independently and lead projects in a multidisciplinary team. The incumbent will lead the development and optimization of noval cell therapy processes. This incumbent will support and lead the technology transfer of developed cell therapy processes to GMP mafanucturing or external partners.


Required: Bachelor's degree in a related field.

Preferred: MS or Ph.D. in related scientific /engineering field.


Required: Seven years of relevant experience to include three years of supervisory or managerial experience. With Master's degree, five years of required experience to include four years of lead or supervisory experience.


•5+ years of experience in process development of cell therapy or other biologics modalities.

•Experience in PD laboratory operations with cell therapy experience prefered. Experience includes primary cell culture, G-Rex, Wave bioreactor, CliniMACS Prodigy, Lovo, and other noval cell therapy devices.

•Demonstrated ability to collaborate effectively in a multi-disciplinary team.

•Demonstrated strong communication skills, interpersonal skills and a superior drive for results.

•Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff.

•Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.

•Ability to operate as an effective tactical, as well as strategic thinker.

•Ability to coach and influence junior level scientists and associates.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.

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