Postdoctoral Research Associate

Location
Washington University in St. Louis, MO
Salary
salary based on years of experience and provides postdoctoral benefits
Posted
September 15 2020
Ref
McNeill
Position Type
Full Time
Organization Type
Academia
Job Type
Postdoc

REQUIRED QUALIFICATIONS:

· Ph.D. degree.

· Demonstrated relevant research experience.

· Excellent communication skills and the ability to work in collaboration.

PREFERRED QUALIFICATIONS:

· Strong background in molecular biology, developmental biology, or cell biology.

· Experience in RNA-seq, ChIP-seq, or Hi-C is a plus.

Postdoctoral Research Associate Position open in the McNeill Lab (Department of Developmental Biology)

Outstanding applicants are sought at the level of Postdoctoral Research Associate/Scholar in the McNeill lab to study how the nuclear envelope regulates gene expression during reprogramming from oocytes to early embryos. This project centers on a poorly studied protein, Nemp, that we recently found is critical for fertility in flies, worms, fish and mice (Tsatskis et al., 2020). Our studies indicate that NEMP1 supports nuclear envelope stiffness, and that loss of Nemp1 leads to defects in chromatin organization.

Overview of the McNeill Lab:

A central challenge in biology is to understand how cells become organized into tissues, and how tissue growth is coordinated with tissue organization. The McNeill lab combines genetic screens, high-resolution imaging and biochemical dissection of signaling pathways in flies, mice and hydra to uncover these basic and conserved mechanisms. A focus in the laboratory is to understand how Fat cadherins function in Hippo pathway-regulated growth control, planar cell polarity (PCP) tissue organization and metabolism. Fat cadherins are enormous cell adhesion molecules that bind via cadherin-cadherin interactions to another large cadherin called Dachsous (Ds). The Hippo pathway is a highly conserved signaling pathway that regulates proliferation and apoptosis via control of the activity of the transcriptional co-activators Yorkie/YAP. We use the fly eye, wing, testes and ovaries and the mouse kidney as models for dissecting the function of these pathways. Tweets by McNeillLabWU

REQUIRED QUALIFICATIONS:

· Ph.D. degree.

· Demonstrated relevant research experience.

· Excellent communication skills and the ability to work in collaboration.

PREFERRED QUALIFICATIONS:

· Strong background in molecular biology, developmental biology, or cell biology.

· Experience in RNA-seq, ChIP-seq, or Hi-C is a plus.

SALARY RANGE:

Base pay commensurate with experience.

PRE-EMPLOYMENT SCREENING:

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

DEPARTMENT SUMMARY:

About the Department of Developmental Biology:

The Department of Developmental Biology is a dynamic research community, with interests spanning multiple model organisms and disease paradigms, and the research environment and facilities at Washington University and the School of Medicine is world-class.

BENEFITS:

This position is eligible for full-time benefits. Please click the following link to view a summary of benefits: https://hr.wustl.edu/benefits/.

APPLICANT SPECIAL INSTRUCTIONS:

Review of applications will start September 1, 2020. Interested applicants should email a single PDF file consisting of a cover letter, curriculum vitae, a personal statement (including research interests and career goals) and should arrange for submission of three letters of reference to Dr. Helen McNeill at mcneillh@wustl.edu. More information on the McNeill lab can be found at https://mcneilllab.wustl.edu.

Information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs.

EOE STATEMENT:

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

 

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