Post Doctoral Fellow in Alzheimer's Research
A NIH funded postdoctoral position is available immediately in the Wisniewski Lab at New York University to study the role of apolipoprotein E in Alzheimer’s disease pathogenesis in a multidisciplinary team. This position is funded by a NIH P01 program grant. The successful candidate will use a combination of neuropathological, proteomic and cell culture techniques to identify novel proteins that mediate the pathological role of apoE in Alzheimer’s disease.
We have recently developed new proteomics approaches that have allowed us to examine pathogenesis of Alzheimer’s disease directly in human brain tissue samples. This project uses novel proteomics approaches to identify the proteins that are differentially associated with amyloid pathology in apoE2, apoE3 and apoE4 in human brain tissue. This is an outstanding opportunity to work independently on a high impact, state-of-the-art project in a stimulating vibrant research environment. We are looking for highly motivated creative individuals for our multidisciplinary team of scientists. International candidates are welcome to apply.
- PhD or equivalent in neuroscience, neuropathology or neurodegenerative disease
- Experience in microscopy, cell culture and protein assay techniques
- Independent conduct and development of research projects
- Excellent scientific productivity evidenced by high-quality publications
- Excellent communication and interpersonal skills
- Prior experience in Alzheimer’s disease research
- A strong interest in proteomics and/or bioinformatics. Prior experience is not a pre-requisite as there is ample of training opportunities for a motivated individual.
- Perform laser capture microdissection on human tissue samples
- Characterize and analyze neuropathology present in human tissue samples
- Work closely with the proteomics mass spectrometry team that is led by Dr. Beatrix Ueberheide to analyze the proteome of neuropathological lesions.
- Perform mechanistic and cell culture studies to understand how the novel protein candidates from the discovery mass spectrometry study influence the development of amyloid and tau pathology.
NYU School of Medicine is one of the nation’s top-ranked medical schools. For 175 years, NYU School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health, the School of Medicine at its core is committed to improving the human condition through medical education, scientific research, and direct patient care. NYU School of Medicine is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sex, sexual orientation, transgender status, gender dysphoria, national origin, age, religion, disability, military and veteran status, marital or parental status, citizenship status, genetic information or any other factor which cannot lawfully be used as a basis for an employment decision.
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