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Doctoral Researcher (f/div/m) in Bioinformatics

Job Details

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – (Leibniz-HKI, www.leibniz-hki.de) investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The Research Group Systems Biology and Bioinformatics invites talented and highly gifted candidates to apply as a

Doctoral Researcher (f/div/m) in Bioinformatics

for three years initially.

The Systems Biology & Bioinformatics (SBI) group of the Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (Leibniz-HKI), Jena, Germany, is seeking a Doctoral Researcher in the domain of multi-omics integration to develop novel therapeutic treatments for infectious diseases. SBI is active participant of several national and international collaborative efforts to tackle infectious diseases. The successful candidate is expected to analyze transcriptomics, metabolomics and clinical data to identify host biomarker signatures that would enable (i) the early diagnosis of infection and sepsis that can trigger early pre-symptomatic treatment; (ii) the stratification of sepsis patients to target with novel therapies; (iii) the design of combinatorial therapies that will be validated by our collaborators in preclinical and clinical studies. The successful candidate is expected to interact closely with wet-lab scientists and clinicians for discovering new molecular mechanisms of pathogens.

Your profile:

  • MSc degree in Systems Biology, Computational Biology, Bioinformatics, Biophysics, Computer Science or a related discipline
  • Knowledge and experience in the analysis of biological high-throughput data
  • Knowledge in statistical methods in the context of biological systems
  • Programming experience (Python, Perl, C++, R).
  • Well-developed collaborative skills

A strong interest in conducting collaborative research on the topic outlined above is paramount. Candidates are expected to be interested in working at the boundaries of several research domains.
 

We offer: The successful candidates will be hosted at HKI’s SBI group. We offer an international and multi-disciplinary environment with a strong expertise in the proposed research field and a convivial working atmosphere in an interdisciplinary and international research environment. Currently the group consists of approximately 17 members at different levels of seniority.

SBI is coordinating a Horizon 2020 Marie Curie Innovative Training Network and is an active participant of the Cluster of Excellence “Balance of the Microverse” and CRC/ Transregio 124 “Pathogenic fungi and their human host: Networks of interaction” funded by the Deutsche Forschungsgemeinschaft. More information on the research output of the group can be found here.
 

Life in Jena:

  • Jena is a city with high quality of life, central for trips to major cities (Weimar, Leipzig, Dresden, Berlin, Munich) and surrounded by beautiful nature, perfect for hiking, biking and winter sports
  • Jena was awarded the title "City of Science" from the Stifterverband für die Deutsche Wissenschaft in 2008.
  • The city is also a hub for notable life science companies, enabling the transfer from academia to industry.

Salary is paid according to German TV-L (salary agreement for public service employees). As an equal opportunity employer the Leibniz-HKI is committed to increasing the percentage of female scientists and therefore especially encourages them to apply.

For further information:

Assoc. Prof. Dr. Gianni Panagiotou | +49 3641 532 1759 | career@leibniz-hki.de

Applications:

Complete applications in English should include a cover letter, a CV containing a complete list of publications, a brief statement of research experiences, the addresses of two possible referees, and should be submitted by August 31, 2020, via the Leibniz-HKI online application system.

Company

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – was founded in 1992 and has been a member of the Leibniz-Association since 2003.

The scientists at the HKI carry out research into natural products from micro-organisms and into the infection biology of pathogenic fungi. Novel discoveries of natural products are investigated for their biological activity and modified purposefully for possible drug applications. In this context, the institute has been maintaining a rich tradition in Jena bringing in cutting-edge approaches to solutions and research methods beyond that.

The HKI is firmly integrated into the most important Thuringian research centre, the Beutenberg Campus Jena. Beyond the close corporation with the neighbourhood institutes, we collaborate intensively with the Friedrich-Schiller-University Jena, the Jena University Hospital and the University of Applied Sciences Ernst-Abbe in Jena. This leaves a link in numerous joint research projects and a strong commitment of our staff to academic teaching.

Approximately 380 members of staff are currently employed at the HKI. Further structural units possessing an integrative function and including independent junior research groups and cross-disciplinary institutions are organized around five scientific departments and the Bio Pilot Plant.

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