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Postdoctoral Training in the Structural Biology and Biochemistry of Gene Regulation

University of Texas Southwestern Medical Center
Dallas, Texas (US)
Competitive pay and benefits commensurate with the applicant’s level of experience.
Closing date
Apr 6, 2020


Dr. W. Lee Kraus and Dr. Yunsun Nam are currently seeking applicants with a Ph.D. degree for joint postdoctoral training in The Laboratory of Signaling & Gene Regulation and The Laboratory of RNA Biochemistry, respectively, within the Cecil H. and Ida Green Center for Reproductive Biology Sciences.

We are seeking a trainee interested in studying RNA/protein complexes who will initiate and execute research projects investigating the molecular mechanisms by which RNAs and proteins assemble into specific complexes for particular biological functions.  The goal is to determine how macromolecular recognition and enzymatic regulation are accomplished, using biochemistry, structural biology, and molecular biology.  The position will also include opportunities to learn and use genomics and bioinformatics, as well as cell and animal models.  The Center also provides significant opportunities to engage in clinical/translational projects with clinicians working in the center.

The research in the Nam lab addresses a wide range of questions surrounding RNA-mediated mechanisms in gene expression, using various biochemical and structural approaches, including X-ray crystallography, NMR spectroscopy, cryo-electron microscopy (cryo-EM), fluorescence spectroscopy, high-throughput chemical screens, enzymology, and molecular biology. The research in the Kraus lab covers a broad array of topics, including signaling, gene regulation, and genome function, especially in the areas of chromatin, transcription, epigenetics, RNA biology, and nuclear endpoints of cellular signaling pathways.  The Kraus lab uses a wide variety of model systems and experimental approaches, including biochemistry, molecular biology, structural biology, animal models, genomics, proteomics, bioinformatics, and computational biology. As a joint postdoctoral fellow, the trainee will have immediate access to all the resources and expertise in both of the laboratories.

Candidates should submit a CV or resume, a brief statement of interests and accomplishments, and a list of three references in one file (preferably .pdf) by e-mail to Successful applicants will receive competitive pay and benefits commensurate with the applicant’s level of experience.

Website for Kraus lab:

Website for Nam lab:

UT Southwestern Medical Center is an Affirmative Action/Equal Opportunity Employer.  Women, minorities, veterans and individuals with disabilities are encouraged to apply.

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