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Project Development Scientist - Brain Tumor Immunotherapy

Employer
City of Hope
Location
Duarte, California
Salary
Competitive
Closing date
Mar 4, 2020

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Discipline
Life Sciences
Position Type
Full Time
Organization Type
Healthcare/Hospital

Job Details

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
AProject Development Scientist position is available at Beckman Research Institute of City of Hope and will be part of the Clinical and Translational Project Development Core supporting project management for a California Institute of Regenerative Medicine (CIRM)funded clinical trial, grant reporting, future grant submissions and manuscript writing. This Project Development Scientist will be affiliated with the Brain Tumor Cellular Immunotherapy Program led by Dr. Christine Brown, focusing on translational development of brain-tumorspecific chimeric antigen receptor (CAR) T cell therapies. S/he will work closely with program-associated laboratory and clinical researchers, regulatory staff and biostatisticians to shepherd projects from conception to grant funding, to clinical trial, to manuscript.

Key Responsibilities include:

  • CIRM Project Management: Scientist will manage timelines, all site visits, and quarterly progress reporting for a CIRM CLIN 2 grant funding an ongoing clinical trial of IL13R?2 CAR T cells for brain metastatic disease. Develop In-depth Knowledge of Cellular Immunotherapy Program Research Goals and Areas of Emphasis: Scientists are expected to become well-versed in the terminology, biology and treatments associated with the Cellular Immunotherapy Center. Scientists will attend Cellular Immunotherapy Center Disease Team meetings, Brown laboratory pre- linical research data meetings, and relevant seminars and conferences to gain a thorough familiarity with the ongoing research interests of the Immunotherapy Center.
  • Project Design and Grant Writing: Scientist will assist and advise members of Dr. Brown's team in design and preparation of new projects for funding as well as managing the logistics of grant submission. They will help match investigators to appropriate grant opportunities throughout the stages of project and career development. They will edit/write portions of the grant text and frame the project as appropriate for the specific application. They will also assist in preparing grant progress reports for grants that have been awarded.
  • Clinical Protocol Writing and Submission: Scientists will work with the protocol design team (laboratory and clinical investigators, biostatisticians, research nurses, investigational pharmacists) on clinical trial design and protocol preparation for brain tumor cellular immunotherapy investigator- initiated early-phase clinical trials. Scientists will interface with Research Support Services to develop consent forms. For translational projects involving a City of Hope-held Investigational New Drug Application (IND), they will provide and review text and figures for IND submission.
  • Manuscript Writing and Public Access Compliance: Scientists will advise and assist investigators with interpretation and presentation of clinical /translational data for publication, and edit/write portions of the manuscript text. They will also ensure that the appropriate funding agencies and the City of Hope Comprehensive Cancer Center Support Grant are acknowledged, and that NIH-funded manuscripts are archived in PubMed Central.

Basic education, experience and skills required for consideration:

  • Master's degree, Ph.D., preferred.
  • With a Ph.D., two (2) years of experience in scientific writing, clinical study management, or clinical trial regulatory experience in a healthcare/research/academic environment; or
  • With a master's degree, five (5) years of related experience.
  • Excellent, organizational, scientific writing, communication, and interpersonal skills are key.

Preferred education experience and skills:

  • Ph.D.in the biological/chemical sciences.
  • Prefer experience in NIH or DOD research grant writing (R01 level, not post-doctoral fellowships),
  • Involvement with human observational or therapeutic studies, protocol design/writing for human sample, observational/retrospective or therapeutic studies, translational project management.
  • Familiarity with data analysis techniques, graphing methods, and interpretation of laboratory and clinical data.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

Company

City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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