(Contract) Research Associate, Analytical Operations

The Role:
The primary responsibilities of this role will be to support development and performance of analytical methods for messenger RNA therapeutic drug substance and drug products. The incumbent will be expected to undertake laboratory work to support testing and data collation. Additional responsibilities include developing high throughput methods using liquid handling and end-to-end sample tracking for drug substance/product components and impurities. This position will support cross-functional teams in Research and Development, Production and Quality. Additionally it is expected that the role will require the individual to generate technology transfer documents and enable the physical transfer of methods to receiving groups as part of a broader functional responsibility. The anticipated time frame for this assignment is six months.

Here's What You'll Do:

• Undertake analytical testing using established methods to generate high quality data to support process development.
• Develop high throughput methods in collaboration with supervisor and perform verification and validation experiments.
• Work with digital teams to enable end-to-end sample tracking from submission to final report of submissions.
• Write analytical method SOP and train personnel on methods as needed.
• Provide summary presentations and detailed reports to internal and external stake holders.
• Maintain and troubleshoot equipment performance as needed.
• Technology transfer of high throughput analytical methods to receiving partners, e.g. preclinical QC, non-GMP and GMP stability.
• Provide subject matter expertise to support functions for methods that have been transferred.

Here's What You'll Bring to the Table:

• BS with 1-3 years or MS with 0-2 years of relevant industry experience.
• BS/MS in Analytical Chemistry, Biochemistry, Chemical Engineering, or closely related field.
• Knowledge and extensive hands-on experience of HPLC and modes of separation (e.g. ion exchange, reverse phase ion pairing, size exclusion). Knowledge of biophysical techniques, GC/MS and LC/MS is a plus.
• Knowledge and extensive hands-on experience of equipment platforms (e.g. Thermo, Waters, Agilent) and data processing software (e.g. Chromeleon, Empower and Openlab).
• Familiarity with electronic notebooks, LES and LIMS
• Knowledge of nucleic acid chemistry and biology and standard methods of analysis of these molecules.

Why join Moderna Therapeutics

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit www.modernatx.com .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.

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Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.